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Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase
(19.01.2023)
Invasive fungal infections (IFIs) are increasing as major infectious diseases
around the world, and the limited efficacy of existing medications has resulted in
substantial morbidity and death in patients due to the lack ...
New imidazole derivatives as aromatase inhibitor: Design, synthesis, biological activity, molecular docking, and computational ADME-Tox studies
(06.01.2023)
In this study, a series of imidazole derivatives was designed, synthesized, and evaluated for in vitro bi-
ological activity on the human breast cancer cell line MCF7 by MTT assay. To determine the selectivity
of the ...
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)
Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate
(DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ...
Enhanced Method for the Synthesis and Comprehensive Characterization of 1‑(4-Phenylquinolin-2-yl)propan-1-one
(2023)
We present an enhanced method for synthesizing a
novel compound, 1-(4-phenylquinolin-2-yl)propan-1-one (3),
through the solvent-free Friedländer quinoline synthesis using
poly(phosphoric acid) as an assisting agent. ...
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(Wiley-VCH GmbH, Weinheim, 2021/4)
A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the
phenylurea unit was synthesized and tested against some metabolic enzymes
including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), ...
Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
(19 Jan 202)
Pathological angiogenesis plays a critical role in tumorigenesis and tumor pro gression, and anti-angiogenesis therapies have evinced promising antitumor
effects in solid tumors. Chalcone skeleton has been regarded as a ...
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)
The combination of a commercially available PGLA
(poly[glycolide-co-L-lactide]), 90:10% suture material with bio active bioglass nanopowders (BGNs) and graphene oxide (GO)-
doped BGNs offers new opportunities for the ...
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(2023)
Mushrooms, which have been collected to meet the nutritional needs of the world for many years,
have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies
carried out to determine ...
Machine Learning Approaches for One-Day Ahead Soil Temperature Forecasting
(2023)
Present study investigates the capabilities of six distinct machine learning techniques such as ANFIS network with fuzzy c-means (ANFIS-FCM), grid partition (ANFIS-GP), subtractive clustering (ANFIS-SC), feed-forward neural ...
The effect of the Ebe Evimde application on the self-efficacy and anxiety levels of mothers: Randomized controlled trial
(DIGITAL HEALTH, April 25, )
Objective: Family health can be improved by making home visits with mobile applications. This study was carried out to
evaluate the effect of a mobile application and web-based software called Ebe Evimde (My Home Midwife), ...