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1, 2, 3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
(Taylor & Francis, 2022/01/26)
In recent years, acetylcholinesterase (AChE) and α-glycosidase (α-gly) inhibition have emerged as a promising and important approach for pharmacological intervention in many diseases such as glaucoma, epilepsy, obesity, ...
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
(Elsevier, 2022/12/05)
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds ...
Synthesis and biological evaluation of thiosemicarbazone derivatives
(Springer US, 2022/07/21)
In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were ...
Biological effects and molecular docking studies of Catechin 5-O-gallate: Antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Taylor & Francis, 2022/04/13)
Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ...
The synthesis and characterization of iron nanoparticles with lemon peel and its use in magnetic solid phase extraction for trace levels of lead (II)
(Springer, 03/03/2022)
In this study, a new magnetic solid phase extraction method (MSPE) was developed for the enrichment and separation of
trace amount Pb(II) on the magnetic nanoparticles synthesized using lemon peel (
Fe3O4-LP). The ...
Removal of sulfadiazine from aqueous solution by magnetic biochar prepared with pomegranate peel
(Taylor&Francis, 17/05/2022)
Magnetic biochar (Fe3O4-BCPP) was prepared by using iron oxide nanoparticles, and biochar which is obtained from pomegranate peel. The Fe3O4-BCPP were characterized by Brunauer-Emmett-Teller analysis, X-ray diffraction ...
ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
(April, 202)
Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is
very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is
aimed ...
Development of quantum dot-phthalocyanine integrated G-quadruplex /double-stranded DNA biosensor
(Elsevier, 2022)
In the present study, the phthalocyanine (Pc) integrated mercaptopropionic acid capped quantum dot
(mpa@QD) biosensor has been developed for the quantitative determination of G-quadruplex and doublestranded
DNA. The ...
Exergy Analysis of Graphene-Based Nanofluids in a Compact Heat Exchanger
(TURKISH SOCIETY OF THERMAL SCIENCES AND TECHNOLOGY, 2022)
In this study, the exergy analysis of graphene-based nanofluids in a compact heat exchanger is examined. In experiments using distilled water as the base fluid, graphene nano-ribbon and graphene oxide nanofluids were used ...
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)
Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ...