Browsing Sivas Cumhuriyet Üniversitesi Eczacılık Fakültesi by Access Type "info:eu-repo/semantics/openAccess"
Now showing items 1-20 of 84
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1, 2, 3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
(Taylor & Francis, 2022/01/26)In recent years, acetylcholinesterase (AChE) and α-glycosidase (α-gly) inhibition have emerged as a promising and important approach for pharmacological intervention in many diseases such as glaucoma, epilepsy, obesity, ... -
A new method for synthesis of carbon nanoparticle and its applications
(2022)In the present study, we synthesized carbon nanoparticles with a different method using chi tosan, a natural polymer. As a result, carbon nanomaterials were diffused directly through the intestinal membrane, and carbon ... -
ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
(April, 202)Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is aimed ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
(December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
(April 2022)Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential ... -
Antioksidan Miktarını Total Olarak Tayin Etme Yöntemleri
(31.12.2023)Zararlı serbest radikallere karşı savaşan ve hücreleri koruyan moleküller olan antioksidanlar tüm canlıların hayatta kalması için hayati önem taşır. Bu da bilim insanlarını, gıdaların antioksidan özelliklerini ölçme ... -
Application of a new dithizone grafted polymeric adsorbent for solid phase microextraction of manganese and copper prior to FAAS in fortified vegetables and barbecue samples
(13.06.2022)A new potential solid phase material called as dithizone@PAA was synthesized for first times, characterized and utilized as an easy versatile polymeric sorbent for the shake-assisted dispersive solid-phase micro-extraction ... -
Application of cloud point extraction for residues of chloramphenicol and amoxicillin in milk samples by HPLC–DAD
(Springer, 2022)A pre-concentration and sensitive determination method for residues of Chloramphenicol (CLP) and Amoxicillin (AMX) in milk samples were developed based on cloud point extraction (CPE) and HPLC–DAD analysis. CLP and AMX ... -
Application of magnetic solid‑phase extraction for sensitive determination of anticancer drugs in urine by means of diamino benzidine tetrachlorohydrate modified magnetic nanoparticles
(Şubat, 202)Background The analysis of drug active molecules and residues in the treatment of cancer is important for the sustainability of human life and therapeutic effects. For this purpose, a new magnetic sorbent was developed ... -
Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
(19 Jan 202)Pathological angiogenesis plays a critical role in tumorigenesis and tumor pro gression, and anti-angiogenesis therapies have evinced promising antitumor effects in solid tumors. Chalcone skeleton has been regarded as a ... -
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
(EYLÜL 2023)Abstract: Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1- methallyl-3-(3,4,5 ... -
Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
(Elsevier, 14.08.2022)Based on the biologically active heterocycle compounds, a series of new benzimidazole-hydrazone deriva- tives ( 3a-3j ) were synthesized, starting from 4-(6-chloro-1 H -benzimidazol-2-yl) benzohydrazide. The syn- thesized ... -
Bioactive Loaded Novel Nano-Formulations for Targeted Drug Delivery and Their Therapeutic Potential
(MDPI, 2022)Abstract Plant-based medicines have received a lot of attention in recent years. Such medicines have been employed to treat medical conditions since ancient times, and in those times only the observed symptoms were used ... -
Biological effects and molecular docking studies of Catechin 5-O-gallate: Antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Taylor & Francis, 2022/04/13)Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ... -
BİYOLOJİK VERİTABANLARI KULLANILARAK BAKTERİYEL TOPOİZOMERAZ I HEDEFLİ TERAPÖTİK DNA APTAMERİ GELİŞTİRİLMESİ
(TÜSEB, 16.05.2023)DNA topoizomerazlar DNA topolojisini değiştirerek replikasyon ve transkripsiyon gibi canlılığı doğrudan ilgilendiren metabolik olaylarda görev alırlar. Bu nedenle kontrolsüz hücre bölünmesi/kanser ve patojenler ile savaşta ... -
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
(2021/6)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
Comparative analysis of pre-fermentation treatments on phenolic compounds and bioactivity in Vitis Vinifera var. Syrah and var. Cabernet Sauvignon grapes
(Mayıs 2023)This study investigated the effect of pre-fermentation treatments on the phenolic compounds and biological activities of red grapes of Vitis vinifera var. Syrah and var. Cabernet Sauvignon Syrah and Cabernet sauvignon musts ... -
Comparison of Chemical Profiles of Aronia melanocarpa Fruit Extracts
(Şubat 2023)The chokeberry plant, which is native to North America and the south of Canada, is a deciduous, shrub-shaped, berry-like plant belonging to the Rosaceae family, which survives for many years. It is seen as a plant that ... -
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(HAZİRAN 20)ABSTRACT: Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to ... -
Decolourization of Methylene Blue in Aqueous Solution by Photocatalytic Oxidation, Fenton Oxidation and Biosorption
(Cumhuriyet Science Journal, 27.12.2022)The aim of the study was to investigate decolourization of Methylene Blue (MB) in aqueous solution using advanced oxidation processes (AOPs) and biosorption comparatively. Photocatalytic decolourization of MB was studied ...