Browsing Sivas Cumhuriyet Üniversitesi Sağlık Bilimleri Fakültesi by Access Type "info:eu-repo/semantics/closedAccess"
Now showing items 1-20 of 21
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Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ... -
Awareness, worry, and hope regarding climate change among nurses: A cross-sectional study
(2023)ABSTRACT Purpose: The aim of this study is to determine nurses’ awareness, worry and hope levels about climate change. Design and Methods: This cross-sectional study was conducted with 511 nurses. Data were collected ... -
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 15.09.2023)Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The resin obtained from this plant is effective for different diseases. The chemical content of the ethanol extract ... -
Cytotoxic effect, spectroscopy, DFT, enzyme inhibition, and moleculer docking studies of some novel mesitylaminopropanols: Antidiabetic and anticholinergics and anticancer potentials
(Elsevier, 2021)b-Amino alcohols (2–4) used in this study were re-synthesized in accordance with our previous study. All compounds were characterized by the combination of NMR, UV–Vis, IR experimental and theoretical spectral data. Then, ... -
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(Begell House Inc., 2023)Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to determine ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)The main aims of anticancer drug development studies is to reduce the toxicity of the developed compound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)The main aims of anticancer drug development studies is to reduce the toxicity of the developed com- pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
The effects of patient education in lithium therapy on quality of life and compliance
(W B SAUNDERS CO, 2003)The purpose of this study was to show the effects of education on medication compliance, symptom level and quality of life of outpatients who were being treated with lithium for bipolar disorder. The study was performed ... -
Evaluation of pressure ulcer risks in patients with the cerebrovascular disease
(UNIVERSITATSVERLAG ULM GMBH, 2007)It is known that patients with neurologic disorders are at high risk for the development of pressure ulcers. The most effective approach in pressure ulcers is the identification of patients at risk and their prevention. ... -
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 05.09.2023)We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ... -
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were ... -
In vitro cytotoxic effects, in silico studies, some metabolic enzymes inhibition, and vibrational spectral analysis of novel β-amino alcohol compounds
(Elsevier, 05.02.2023)In this study, an efficient single-step method for the preparation of β-amino alcohols ( 1 –3 ) in aqueous media was applied. The aim was to investigate the cytotoxic activity of Compounds 1, 2 and 3 in neu- roblastoma ... -
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(MDPI, 01.12.2023)Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body. Objectives: In this study, we aimed to investigate the relationship between ... -
Investigation of Effect on Activities of Daily Living and Symptoms in Hemodilaysis Patients
(Wolters Kluver, 2021)Hemodialysis patients develop many physical and psychosocial symptoms associated with chronic kidney disease and its treatment. The presence of these symptoms also adversely affects an individual’s activities of daily ... -
INVESTIGATION OF THE ANTIMICROBIAL AGENT POTENTIAL OF 1,5-DIKETONE DERIVATIVES
(2021)In this study, 1,5-diketones were synthesized by adding of cyclohexanone to five different chalcone derivatives (1a-e) via the 1,4-Michael addition reaction. Antimicrobial activities of synthesized compounds were investigated ... -
Kadın Sağlığını Koruma ve Geliştirme
(İstanbul Tıp Kitabevleri, 2022)Yaşamlarının hangi döneminde olur sa olsun kadınların sağlığını geliştirmek için; sağlık profesyonelleri, birinci ba samak sağlık çalışanları ve özellikle de hemşireler tarafından sağlıklı beslenme, düzenli egzersiz, ... -
Postoperative Telenursing During the COVID-19 Pandemic: Improving Patient Outcomes
(Journal of PeriAnesthesia Nursing, August, 20)Purpose: This study was conducted to determine if postoperative nurse-driven telehealth visits for patients undergoing septorhinoplasty decreased patient anxiety while improving comfort and satisfaction levels. Design: ... -
Prevalence and factors associated with surgery anxiety in hospitalized patients: a point‑prevalence study
(Irish Journal of Medical Science, October, 2)Background Preoperative anxiety is a challenging problem in the preoperative care of patients. Identifying risk factors helps nurses provide psychological support during the pre-operative visit so that stress can be ... -
Synthesis of PEGylated nanographene oxide as a nanocarrier for docetaxel drugs and anticancer activity on prostate cancer cell lines
(SAGE Publishing, 2021)Graphene oxide (GO) has recently been considered one of the most promising carbon derivatives in nanotechnology. It has many excellent features such as tumor targeting ability, biocompatibility and low toxicity. Therefore, ...