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Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
(The Royal Society of Chemistry, 2 November)
Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host
cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals.
Inhibition ...
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
(Elsevier, 15/09/2021)
In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were characterized ...
Are clarithromycin, azithromycin and their analogues effective in the treatment of COVID19?
(2021)
BACKGROUND: SARS-CoV-2, which started in Wuhan and later affected the whole world, is the most
important disease of the world today. Many ways to inhibit SARS-CoV-2 virus are sought to prevent the
spread of this virus. ...
Could boron-containing compounds (BCCs) be effective against SARS-CoV-2 as anti-viral agent?
(2021)
BACKGROUND: Seven dioxaborole compounds are investigated in this study. Structural and spectral
characterizations are done at the M062X/6-31+G(d,p) level in water. Active sites of these compounds are
determined by contour ...
Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
(De Gruyter, 2021)
Objectives: The aim of this study was to investigate BAP1,
OGT and YY1 genes and protein levels in 12 samples
(8 males, 4 females) of eyelid tumor tissue with basal cell
carcinoma (BCC) and 12 normal control subjects ...
Could Peganum harmala be effective in the treatment of COVID-19?
(2021)
BACKGROUND: Predominant molecules in Peganum harmala leaves were detected using gas
chromatography-mass spectrometry (GC-MS). Based on the results of this analysis, most alkaloids,
fl avonoids and triterpenoids in found ...
Determination of inhibitor activity of drugs against the COVID-19
(2021)
BACKGROUND: It is the SARS-CoV-2 virus, one of the most signifi cant diseases of today’s world. Due to the
high transmission of this disease, studies are ongoing to discover an inhibitor drug that can stop this disease.
In ...
New anti-viral drugs for the treatment of COVID-19 instead of favipiravir
(2021)
The SARS-CoV-2 virus is a major problem in the world right now. Currently, all the attention of
research centers and governments globally are focused on the investigation of vaccination studies and
the discovery of small ...
Could boron compounds be effective against SARS-CoV-2?
(2021)
BACKGROUND: Seven dioxaborole compounds are investigated in this study. Structural and spectral
characterization is done at M062X/6-31+G(d,p) level in the water. Active sites of these compounds are
determined using ...
Cancer antigen-125 is a predictor of mortality in patients with pulmonary arterial hypertension
(ELSEVIER, 2021)
Background: Carbohydrate antigen 125 (CA 125), known as a tumor marker for ovarian cancer, has been reported
to increase and be associated with severity in heart failure and chronic obstructive pulmonary disease. Patients ...