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Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)
Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ...
Collaborative Clinical Research on Metabolomics
(23.10.2023)
Metabolomics is the scientific study of chemical processes involving metabolites, substrates, intermediates, and namely all reagents and products of cell metabolism. Metabolomics and Clinical Approach will contribute to ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
(Galenos Yayinevi Tic. Ltd., Eylül/2023)
Objective
This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model.
Materials and Methods
Five groups were formed with eight ...
Experimental and theoretical insights about the effect of some newly designed azomethine group‐contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ...
Joint Research on Perinatology
(12.07.2023)
Medical and surgical care have made considerable progress in the last two decades in the care of the mother, fetus, and neonate. Most of the improvement in outcomes has been related to advances in diagnostic and therapeutic ...
Current Topics in Perinatology and Neonatology
(NOVA SCIENCE PUBLISHERS, INC, April 10, )
Medical and surgical care have made considerable progress in the last two decades in the care of the mother, fetus, and neonate. Most of the improvement in outcomes has been related to advances in diagnostic and therapeutic ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In
recent years, ...
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)
Background:
Fibromyalgia is a soft tissue rheumatism characterized by chronic and
widespread musculoskeletal pain at specific points in the body.
Objectives:
In this study, we aimed to investigate the relationship ...
Collaborative Clinical Research on Metabolomics
(23.10.2023)
Metabolomikler nelerdir ve ilişkili klinik durumların güncel literatür eşliğinde araştırılması. Metabolomik analizlerin bu klinik durumlardaki hücresel yollakların araştırılması.
Sıçan Batın içi Endometriozis Modelinde VEGFR1-3 Kinaz İnhibitörü Frukuintinibin Etkisi: VEGF/VEGFR ve Hippo-Yap Moleküllerinin Rolü
(06.04.2023)
Endometriozis, kadınların üreme saglıgı açısından önemli bir sorundur. Endometrioziste
endometrial dokunun uterus dısında yayılması söz konusudur. Agrılı adet, pelvik agrı, agrılı
cinsel iliski, infertilite ve diger ...