Yazar "f77a4d5e-8750-4d4e-b39b-b2efe3e2dd6e" için Sivas Cumhuriyet Üniversitesi Veteriner Fakültesi listeleme
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Angiotensin receptor-neprilysin inhibition by sacubitril/valsartan attenuates doxorubicin induced cardiotoxicity in a pretreatment mice model by interfering with oxidative stress, inflammation, and Caspase 3 apoptotic pathway
Dindaş, Ferhat; Güngör, Hüseyin; Ekici, Mehmet; Akokay, Pınar; Bayçumendur, Füsun Erhan; Doğduş, Mustafa; Yılmaz, Mehmet Birhan (AVES, 2021)Objective: Doxorubicin (DOX) is a well-known cardiotoxic agent, whereas sacubitril/valsartan (Sac/Val) is an effective treatment option in heart failure. In this study, we aimed to evaluate the effect of Sac/Val on ... -
ANTI-INFLAMMATORY AND ANTIOXIDANT EFFECT OF ALLIUM SCORODOPRASUM L. ETHANOLIC EXTRACT (ASE) IN MICE
Ekici, Mehmet; Güngör, Hüseyin; Demir, Tuğba; Ateş, Mehmet Burak; Kumru, Alper Serhat (JAPS, October, 2)The antioxidant and anti-inflammatory properties of Allium species plants have been reported in studies. However, no study was found showing the antioxidant and anti-inflammatory properties of Allium scorodoprasum L. ... -
ANTI-INFLAMMATORY AND ANTIOXIDANT EFFECT OF ALLIUM SCORODOPRASUM L. ETHANOLIC EXTRACT (ASE) IN MICE
Ekici, Mehmet (Journal of Animal and Plant Sciences, October 05)The antioxidant and anti-inflammatory properties of Allium species plants have been reported in studies. However, no study was found showing the antioxidant and anti-inflammatory properties of Allium scorodoprasum L. ... -
Boldine provides protective effect against nephrotoxicity induced by cisplatin in Wistar rats: Role of oxidative stress, inflammation and caspase-3
Ekici, Mehmet (Tech Science Press, 18 May 202)Side effects of cisplatin, especially dose-dependent nephrotoxicity, are major factors limiting its use in cancer. Boldine ((S)-2, 9-dihydroxy-1, 10-dimethoxy-aporphine) is a natural alkaloid known for its strong antioxidant ... -
Cardioprotective Effect of Empagliflozin in Rats with IsoproterenolInduced Myocardial Infarction: Evaluation of Lipid Profile, Oxidative Stress, Inflammation, DNA Damage, and Apoptosis
Ekici, Mehmet; Güngör, Hüseyin; Karayiğit, Mehmet Önder; Turgut, Nergiz Hacer; Koçkaya, Mustafa; Karataş, Özhan; Üner, Aykut Göktürk (PLEIADES PUBLISHING INC, 2022-11-13)—The antidiabetic drug empagliflozin is reported to have many cardioprotective effects. However, no studies have investigated the protective effects of empagliflozin (EMPA) in isoprenaline (ISO)-induced cardiac oxidative ... -
Carvacrol Mitigates Bleomycin Induced Experimental Pulmonary Fibrosis
Ekici, Mehmet (Pleiades Publishing, Ltd., 2023)Idiopathic pulmonary fibrosis (IPF) is a serious progressive pulmonary disease of unknown etiology and high mortality. Carvacrol is a natural phenolic monoterpene with various pharmacological effects, especially antioxidant ... -
Determination of Serum Trace Elements and Oxidative Stress in Bitches with Transmissible Venereal Tumor
Ekici, Mehmet; Ekici, Mehmet (Agricultural Research Communication Center, 2023)Background: This study was conducted to compare the changes in oxidative stress levels with some trace elements in blood serum in healthy bitches and bitches with transmissible venereal tumor (TVT). Methods: A total of ... -
Investigation of changes in serum thiols and neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume/platelet count ratio indices in cats undergoing ovariohysterectomy
Ekici, Mehmet (Revista Cientifica de la Facultad de Ciencias Veterinarias, Universidad del Zulia, 2023)The aim of this study was to investigate complete blood indices [neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume/platelet count ratio ... -
Investigation of the Effects of Glutens on Serum Interleukin-1 Beta and Tumor Necrosis Factor-Alpha Levels and the Immunohistochemical Distribution of CD3 and CD8 Receptors in the Small Intestine in Male Rats
Gümüş, Recep; Uslu, Sema; Aydoğdu, Uğur; İmik, Aybüke; Ekici, Mehmet (SCİELO, 13.09.2021)While the role of cytokines in celiac disease has been investigated in detail, cytokine release in the event of the exposure of healthy subjects to glutens has only recently been studied. This study was aimed at determining ... -
Kaempferol and Isorhamnetin Alleviate Lipopolysaccharide-Induced Anxiety and Depression-Like Behavioral in Balb/C Mice
Ekici, Mehmet (National Documentation Centre (EKT), 2023)The etiology of anxiety and depression is linked to inflammation and oxidative stress. Isorhamnetin and Kaempferol are strong antioxidants with anti-inflammatory neuroprotective properties. This study, it was aimed ... -
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice
Ekici, Mehmet (Informa UK (Taylor & Francis), 2023)Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen (APAP) induced hepatotoxicity is still ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
Ekici, Mehmet (Oxford University Press, 2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
Güngör, Hüseyin; Ekici, Mehmet; Karataş, Özhan; Dik, Burak (20.02.2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Protective Effects of Oxytocin and Progesterone on Paclitaxel-induced Neuropathy in Rats
Ekici, Mehmet; Balkaya, Muharrem (Wolters Kluwer - Medknow, 2021)Objective: Paclitaxel (Ptx), used to treat cancer, still causes neuropathic pain and peripheral neuropathy today. This study was conducted to evaluate the effects of progesterone (Pg) and oxytocin (Oxy) on peripheral ... -
Relationship of Oxidative Stress and Some Blood Parameters with Quarters Affected by Mastitis in Dairy Cows
Ekici, Mehmet (Agricultural Research Communication Center, 2023)Background: This study was conducted to evaluate the relationship between oxidative stress and some blood parameters in different number of quarters affected with and without sub-clinical mastitis (SM). Methods: A total ... -
The influence of sex and age on bone turnover markers in the adult to geriatric Kangal shepherd dogs
Ekici, Mehmet (Wiley (Blackwell Publishing), 2023)Objectives: The objective of this research was to learn more about bone metabolism in intact female and male Kangal shepherd dogs during the aging process following skeletal maturity. It also evaluated the potential ...