Browsing Temel Tıp Bilimleri Bölümü by Access Type "info:eu-repo/semantics/openAccess"
Now showing items 21-40 of 56
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In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were ... -
Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury
(2023)Objectives: Our study aimed to investigate the role of endoplasmic reticulum stress (ER) in brain damage following hepatic ischemia-reperfusion (HIR) injury. Specifically, we characterized the expression of markers of ... -
Investigating the Healing Effect of Hyperici Oleum and Triticum vulgare on Septal Perforation in Rats: A Preliminary Study
(2023)Objective: The aim of this study was to investigate histopathologically the possible beneficial effects of hyperici oleum and Triticum vulgare, having anti-inflammatory, antioxidant, and antiproliferative properties, on ... -
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ... -
ISI ŞOK PROTEİN 70 (HSP70) VE KANSER
(Efe Akademik Yayıncılık, 2022)Kardiyovasküler hastalıklardan sonra ikinci sıradaki ölüm nedeni olarak gösterilen kanserin, insidansı ve ölüm oranı tüm dünyada hızla artmaktadır. Amerikan Kanser Derneği'nin yakın tarihli bir raporuna göre, 2020'de ... -
Long noncoding RNA expression analysis in Crimean Congo hemorrhagic fever patients
(Wiley, 2022)Crimean Congo hemorrhagic fever (CCHF) is an acute viral infection that can cause death. The detection of host transcriptome is important for understanding differences in the pathogenesis of the disease. Long noncoding ... -
Medical Students' Views and Attitudes toward Vaccine Refusal during the COVID-19 Pandemic: A Multicenter Study
(20.04.2024)Background: The rapid development and production of COVID-19 vaccines have raised concerns about their safety and efficacy, which have contributed to vaccine hesitancy among some people. Objectives: This study aimed to ... -
Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process
(2021)Abstract Purpose Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells’ DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality ... -
Mide Kanser ve Omik Tabanlı Analizler
(2022)Çoğu normal doku hücresiyle karşılaştırıldığında kanser hücrelerinde belirgin olarak farklı metabolik yolaklarda değişiklikler görülür. Omik tabanlı veri entegrasyonu, mide kanseri araştırmalarında kapsamlı bir şekilde ... -
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ... -
MİDE KANSERİ VE DENEY HAYVANLARI MODELLEMELERİ
(2022)Mide karsinogeneziyle ilgili çalışmalar için çeşitli mide fenotiplerine sahip çok sayıda hayvan modeli mevcuttur. Mide kanseriyle ilgili mekanizmaları anlamak, önleyici ve terapötik müdahaleler tasarlamak için hayvan ... -
MİDE KANSERİ VE HÜCRE KÜLTÜRÜ
(Efe Akademik Yayıncılık, 2022)Mide kanseri, gastrointestinal tümörlere neden olan, insan hayatı ve sağlığı için ciddi bir tehdit oluşturan yaygın bir hastalıktır. Hücre kültürü tekniği, diğer birçok kanser türünde olduğu gibi, mide kanseri ... -
Nanoparticles with PDT and PTT synergistic properties working with dual NIR-light source simultaneously
(2021)A non-toxic nano system using a cleverly designed dual light can be an important treatment strategy in cancer therapy. Here, we propose a unique concept of synergistic non-toxic nanoplatform, which operates with dual ... -
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)The combination of a commercially available PGLA (poly[glycolide-co-L-lactide]), 90:10% suture material with bio active bioglass nanopowders (BGNs) and graphene oxide (GO)- doped BGNs offers new opportunities for the ... -
PENTİLENTETRAZOL İLE OLUŞTURULAN DENEYSEL EPİLEPSİ MODELLERİ
(Efe Akademik Yayıncılık, 2022)Epilepsi, normal beyin işleyişini kesintiye uğratan öngörülemeyen ve tekrarlayan nöbetler içeren; dünya genelindeki nüfusun yaklaşık % 1 'ini etkileyen en yaygın nörolojik klinik bozukluklardan biridir. Nöbet aktivitesi ... -
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ... -
Preventive effects of Capparis Spinose extract on experimental periodontitis in rats: a histopathological and biochemical study
(2023)This study aimed to assess the effectiveness of Capparis Spinose (CS) in preventing the initiation and pro gression of experimental periodontitis and to evaluate the effect of its on systemic oxidative stress in rats by ... -
Psychometric Properties of the Turkish Validity and Reliability of the Parent Diabetes Distress Scale
(20.03.2023)Objective: The aim of this study was to evaluate the validity and reliability of the Turkish translation of the Parent Diabetes Distress Scale (PDDS). Methods: The PDDS is a 5-point Likert-type scale with 20 items. After ... -
RNA N6-Methyladenosine Pathway Writer Genes Expression Levels and Clinical Severity of Infection in Covid-19 Patients
(2023)Abstract—Epigenetic modifications are known to be effective in the severity and mortality rate of SARS CoV-2 infection. N6-methyladenosin (m6A) is a posttranscriptional modification that is carried out by m6A methyltransferases ... -
Role of lncRNAs in Remodeling of the Coronary Artery Plaques in Patients with Atherosclerosis
(2023)Abstract Introduction Cardiovascular diseases (CVDs) are the leading cause of death worldwide according to World Health Organi zation (WHO) data. Atherosclerosis is considered as a chronic infammatory disease that develops ...