Browsing Temel Tıp Bilimleri Bölümü Makale Koleksiyonu by Issue Date
Now showing items 21-40 of 65
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The use of laboratory parameters and computed tomography score to determine intensive care unit requirement in COVID-19
(2021)Objectives It is vital to determine the intensive care unit (ICU) requirement at an early stage to reduce the mortality rate in COVID-19 patients. The aim of the study was to find reliable predictive markers to determine ... -
A novel therapeutic approach to NASH: Both polyethylene glycol 3350 and lactulose reduce hepatic inflammation in C57BL/6J mice.
(2021)Background. The gut-liver axis is one of the most emphasized topics in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Intestinal microbiota dysbiosis has been shown to be a predictor of disease severity and ... -
Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients
(Wiley, 2021 Nisan)Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular responses of COVID-19. In this study, we aimed ... -
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ... -
Experimental, DFT and MD simulation studies of Mordant Black 11 dye adsorption onto polyaniline in aqueous solution
(Journal of Molecular Liquids, 2022)vjv -
Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model
(NEUROLOGICAL RESEARCH, 2022)khg -
The relationship between serum prolidase activity and histone H3 protein levels and fibromyalgia
(VERDUCI PUBLISHERVIA GREGORIO VII, ROME 186-00165, ITALY, 2022)OBJECTIVE: Fibromyalgia (FM) is a clinical syndrome characterized by prominent physical and psychological impairment and widespread pain on both sides of the body, above and below the waist, and along the axial skeleton. ... -
Long noncoding RNA expression analysis in Crimean Congo hemorrhagic fever patients
(Wiley, 2022)Crimean Congo hemorrhagic fever (CCHF) is an acute viral infection that can cause death. The detection of host transcriptome is important for understanding differences in the pathogenesis of the disease. Long noncoding ... -
A significant association between rs2295190 polymorphism of the ESR1 gene and fibromyalgia syndrome
(CMB Association Publiher, 2022)Fibromyalgia syndrome (FMS) is a multifactorial disease characterized by chronic diffuse pain. Genetic factors are also involved in the etiology. However, there is not enough information on the genetic factors that ... -
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats
(Elsevier, 2022)The toxicity of acetaminophen (N-acetyl-para-aminophenol (APAP)) is the most frequent cause of drug-induced liver damage. Galium aparine L. (GA) is traditionally used to treat jaundice. We aimed to investigate the ... -
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ... -
Death receptor-dependent apoptosis and cell cycle delay induced by bioymifi in human cervical cancer cells
(2022)Abstract: In chemotherapy applied against cervical cancer, non-specific cytotoxicity and drug resistance that develops over time are trying to be overcome. Therefore, the development of effective and innovative chemotherapeutic ... -
PENTİLENTETRAZOL İLE OLUŞTURULAN DENEYSEL EPİLEPSİ MODELLERİ
(Efe Akademik Yayıncılık, 2022)Epilepsi, normal beyin işleyişini kesintiye uğratan öngörülemeyen ve tekrarlayan nöbetler içeren; dünya genelindeki nüfusun yaklaşık % 1 'ini etkileyen en yaygın nörolojik klinik bozukluklardan biridir. Nöbet aktivitesi ... -
MİDE KANSERİ VE HÜCRE KÜLTÜRÜ
(Efe Akademik Yayıncılık, 2022)Mide kanseri, gastrointestinal tümörlere neden olan, insan hayatı ve sağlığı için ciddi bir tehdit oluşturan yaygın bir hastalıktır. Hücre kültürü tekniği, diğer birçok kanser türünde olduğu gibi, mide kanseri ... -
VENÖZ KAN ÖRNEĞİ ALABİLME
(Sivas Cumhuriyet Üniversitesi Rektörlük Matbaası, 2022)Venöz kan alma dünya genelinde sağlık kuruluşlarında en fazla yapılan girişimsel işlemdir. Hastanın tanı almasından tedavisinin düzenlemesi ve takibine kadar olan sü reçte venöz kan testine bağlı sonuçlar önemli bir yer ... -
The 5-HT7 receptor antagonist SB-269970 alleviates seizure activity and downregulates hippocampal c-Fos expression in pentylenetetrazole-induced kindled rats
(NEUROLOGICAL RESEARCH, 2022)Objectives: Recently, studies have demonstrated that serotonin type 7 receptors (5-HT7) have conflincting effects on neuronal excitability in different brain regions. However, the effect of 5-HT7 on seizures has not been ... -
Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells
(Metabolic Brain Disease, 2022)Recent studies have shown that angiotensin-converting enzyme (ACE) inhibitors have reduced oxidative damage in the central nervous system (CNS). Accumulating evidence have also demonstrated that captopril, an ACE inhibitor, ... -
ISI ŞOK PROTEİN 70 (HSP70) VE KANSER
(Efe Akademik Yayıncılık, 2022)Kardiyovasküler hastalıklardan sonra ikinci sıradaki ölüm nedeni olarak gösterilen kanserin, insidansı ve ölüm oranı tüm dünyada hızla artmaktadır. Amerikan Kanser Derneği'nin yakın tarihli bir raporuna göre, 2020'de ... -
Validation of Friedewald, Martin-Hopkins and Sampson low-density lipoprotein cholesterol equations
(2022/5/13)Background: Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration is ... -
Assessment of semaphorin 3A and semaphorin 7A levels in primary Sjogren's syndrome
(Springer, 2022/8/28)Sjogren's syndrome (SS) is a chronic autoimmune connective tissue disease. Varying rates of system involvements may be seen in the course of the disease. Semaphorins has multifunctions in several physiological and pathological ...