Browsing Beslenme ve Diyetetik Bölümü by Author "49554685-9d54-4666-bf83-86d8fb2f7627"
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In vitro cytotoxic effects, in silico studies, some metabolic enzymes inhibition, and vibrational spectral analysis of novel β-amino alcohol compounds
Tas, Ayca; Tüzün,Burak; Khalilov, Ali N; Taslimi, Parham; Agbektas, Tugba; Keklikcioglu Cakmak, Nese (Elsevier, 05.02.2023)In this study, an efficient single-step method for the preparation of β-amino alcohols ( 1 –3 ) in aqueous media was applied. The aim was to investigate the cytotoxic activity of Compounds 1, 2 and 3 in neu- roblastoma ... -
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
Gezegen, Hayreddin; Gürdere, Meliha B.; Dinçer, Ayşegül; Özbek, Oğuz; Koçyiğit, Ümit M.; Taslimi, Parham; Tüzün, Burak; Budak, Yakup; Ceylan, Mustafa (2021)A new class of cyanopyridine derivatives (10a-e and 11a-e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ...