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Now showing items 11-15 of 15
Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles
(TAYLOR & FRANCIS LTD, 2018)
The new 1-(4-(3-(aryl)acryloyl)phenyl)-1H-pyrrole-2,5-diones (5a-g) were prepared from 4-aminchalcones (3a-g) and screened for biological activities. All compounds (3a-g and 5a-g), except 3d and 3e displayed good cytotoxic ...
BIOLOGICAL EVALUATION OF 1-(4-(HYDROXY(1-OXO-1,3-DIHYDRO-2H-INDEN-2-YLI-DENE)METHYL)PHENYL)-3-PHENYLUREA DERIVATIVES: ANTICHOLINERGICS AND ANTIEPILEPTIC POTENTIALS
(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2019)
In this work, a class of phenylurea compounds containing 2-benzoylindan-1-one molecules 3a-3j was designed and synthesized from the reaction of phenylurea-substituted acetophenone compounds with phthalaldehyde molecule ...
Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(-aminoalkyl)phosphinic acid derivatives against human breast cancer
(WILEY, 2017)
The aim of this study was to evaluate biologically active novel molecules having potentials to be drugs by their antitumor properties and by activities of apoptotic caspase and topoisomerase. Following syntheses of novel ...
Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles
(WILEY, 2018)
Some novel derivatives of thiosemicarbazide and 1,2,4-triazole-3-thiol were synthesized and evaluated for their biological activities. The title compounds were prepared starting from readily available pyridine-2,5-dicarboxylic ...
Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep
(WILEY, 2018)
In this work, the carbonic anhydrase (CA) enzyme was purified from Kangal Akkaraman sheep in Sivas, Turkey with specific activity value of 6681.57 EU/mg and yield of 14.90% with using affinity column chromatography. For ...