Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Author "cb684ceb-f3bf-44b7-b801-fb1291fe352f"
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Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
TUTAR, UĞUR; ŞAHİN, NESLİHAN; ÜSTÜN, ELVAN; ÇELİK, CEM; GÜRBÜZ, NEVİN; ÖZDEMİR, İSMAİL (ELSEVİER, 2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
Çelik, Cem; Üstün, Elvan; Şahin, Neslihan; Tutar, Uğur (December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
TUTAR, UĞUR; Çelik, Cem; ÜSTÜN, ELVAN; ÖZDEMİR, NAMIK; Şahin, Neslihan; DAVID, SEMERIL; Gürbüz, Nevin; Özdemir, İsmail (EYLÜL 2023)Abstract: Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1- methallyl-3-(3,4,5 ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
TUTAR, UĞUR; ÜSTÜN, ELVAN; ŞAHİN, NESLİHAN; ÇELİK, CEM; ÖZDEMİR, NAMIK; GÜRBÜZ, NEVİN; ÖZDEMİR, İSMAİL (The Royal Society, 2021)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ...