Browsing Biyoloji Bölümü Makale Koleksiyonu by Author "d11a645a-74bc-4484-a8c8-be7405189fe1"
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A Review of Recent Studies on the Antioxidant and Anti-Infectious Properties of Senna Plants
Durna Daştan, Sevgi (oxidative medicine and cellular longevity, 2022)The use of phytochemicals is gaining interest for the treatment of metabolic syndromes over the synthetic formulation of drugs. Senna is evolving as one of the important plants which have been vastly studied for its ... -
A Review on Tradescantia: Phytochemical Constituents, Biological Activities and Health-Promoting Effects
Durna Daştan, Sevgi (Frontiers in Bioscience landmark, 2022)Tradescantia is a genus of herbaceous and perennial plants belonging to the Commelinaceae family and organized into three infrageneric classifications and 12 sections. More than 80 species within the genus have been used ... -
Biosynthesis of Secondary Metabolites Based on the Regulation of MicroRNAs
Durna Daştan, Sevgi (biomed research international, 2022)MicroRNA (miRNA), a noncoding ribonucleic acid, is considered to be important for the progression of gene expression in plants and animals by rupture or translational repression of targeted mRNAs. Many types of miRNA ... -
Biosynthesized silver nanoparticles and miR34a mimics mediated activation of death receptor in MCF-7 human breast cancer cell lines
Durna Daştan, Sevgi (cancer nanotechnology, 2022)AbstractNano-biotechnology-based clinical applications to cure health-related issues have gained huge attention among the scientific community and hold great promise to limit cancer metastasis. In this study, green-derived ... -
Chemical and functional composition and biological activities of Anatolian Hypericum scabrum L. plant
Durna Daştan, Sevgi (2023)Hypericum scabrum L. plant has wide use in ethnopharmacology and is cultivated both naturally and technologically. This study was conducted to determine chemical and functional properties and in vitro biological activities ... -
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives
Durna Daştan, Sevgi (oxidative medicine and cellular longevity, 2022)Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
Durna Daştan, Sevgi (2023)Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods: Five groups were formed with eight ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
Durna Daştan, Sevgi (2023)Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods: Five groups were formed with eight ... -
Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential
Durna Daştan, Sevgi (oxidative medicine and cellular longevity, 2022)Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum L.) and in wood and bark of some tree ... -
Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
Durna Daştan, Sevgi (evidence based complementary and alternative medicine, 2022)Polyalthia suberosa (Roxb.) is a plant used to cure coughs, dysentery, fevers, joint aches, rheumatic pain, inflammation, and a variety of skin diseases. *e aim of the study was to evaluate the ethyl acetate extract of ... -
Evaluation of mutagenesis, necrosis and apoptosis induced by omeprazole in stomach cells of patients with gastritis
Durna Daştan, Sevgi (cancer cell international, 2022)Background: Gastritis is a superfcial and prevalent infammatory lesion that is considered a public health concern once can cause gastric ulcers and gastric cancer, especially when associated with Helicobacter pylori ... -
Pharmacological effects and therapeutic potential of natural compounds in neuropsychiatric disorders: An update
Durna Daştan, Sevgi (Frontiers Media SA, 2022)Neuropsychiatric diseases are a group of disorders that cause significant morbidity and disability. The symptoms of psychiatric disorders include anxiety, depression, eating disorders, autism spectrum disorders (ASD), ... -
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
Durna Daştan, Sevgi (2023)The cytotoxic activities of the compounds were determined by the 3‐(4, 5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ... -
Potent In Vitro Phosphodiesterase 1 Inhibition of Flavone Isolated from Pistacia integerrima Galls
Durna Daştan, Sevgi (biomed research international, 2022)To prospect an isozyme-specific, effective inhibitor against the physiologically-crucial enzyme phosphodiesterase 1 (PDE1), phytochemicals from Pistacia integerrima galls were screened. The chloroform fraction of gall ... -
The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies
Durna Daştan, Sevgi (Elsevier BV, 2022)Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana L. Preclinical pharmacological studies ... -
The role of Tumour Necrosis Factor in neuroinflammation associated with Parkinson's disease and targeted therapies
Durna Daştan, Sevgi (neurochemistry international, 2022)Neurodegenerative disorders Parkinson’s disease is a progressive neurodegenerative disorder associated with neuroinflammatory responses that lead to the neurodegeneration of the dopaminergic neurons. These neuroinflammatory ... -
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
Durna Daştan, Sevgi (biomed research international, 2022)Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal ... -
Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications
Durna Daştan, Sevgi (evidence based complementary and alternative medicine, 2022)Urtica dioica belongs to the Urticaceae family and is found in many countries around the world. 1is plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, ...