Biyoloji Bölümü Makale Koleksiyonu: Recent submissions
Now showing items 1-20 of 36
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Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
(2023)The cytotoxic activities of the compounds were determined by the 3‐(4, 5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ... -
Chemical and functional composition and biological activities of Anatolian Hypericum scabrum L. plant
(2023)Hypericum scabrum L. plant has wide use in ethnopharmacology and is cultivated both naturally and technologically. This study was conducted to determine chemical and functional properties and in vitro biological activities ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
(2023)Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods: Five groups were formed with eight ... -
Synthesis of novel Cu(II) complexes with N2O2 ligands: Characterization, theoretical calculations, antimicrobial, antioxidant, DNA binding, and in vitro anticancer activity studies
(2023)The aim was to investigate the in vitro antimicrobial, antioxidant, cytotoxic activities and pBR322 Plasmid DNA interaction potentials of newly synthesized Schiff bases and their copper complexes. Cytotoxic activities of ... -
Investigation of gene expression levels in thyroid tissues of rats treated with Wi-Fi electromagnetic wave (2.4–3 GHz Wi-Fi RF-EMF)
(2023)A B S T R A C T In this study, it was aimed to examine the effects of wireless waves applied to rats in the thyroid tissue by evaluating gene expression levels on 12 determined gene regions. 20 healthy 16-week-old Wistar ... -
Phylogenetic analysis of Prunus genus using nuclear and chloroplast gene markers as a bioorganic structure profiling. Abdulrahman SS; Dastan SD; Shahbaz SE; Selamoglu Z. 2023. Journal of Molecular structure, 2023, 1284 DOI10.1016/j.molstruc.2023.135300
(2023)Prunus species are known as model species for the family Rosaceae and other woody plants with their small genome size and relatively small life cycle as woody plants. Also Prunus species are economically important plants ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
(2023)Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods: Five groups were formed with eight ... -
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
(biomed research international, 2022)Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal ... -
The role of Tumour Necrosis Factor in neuroinflammation associated with Parkinson's disease and targeted therapies
(neurochemistry international, 2022)Neurodegenerative disorders Parkinson’s disease is a progressive neurodegenerative disorder associated with neuroinflammatory responses that lead to the neurodegeneration of the dopaminergic neurons. These neuroinflammatory ... -
A Review on Tradescantia: Phytochemical Constituents, Biological Activities and Health-Promoting Effects
(Frontiers in Bioscience landmark, 2022)Tradescantia is a genus of herbaceous and perennial plants belonging to the Commelinaceae family and organized into three infrageneric classifications and 12 sections. More than 80 species within the genus have been used ... -
Biosynthesized silver nanoparticles and miR34a mimics mediated activation of death receptor in MCF-7 human breast cancer cell lines
(cancer nanotechnology, 2022)AbstractNano-biotechnology-based clinical applications to cure health-related issues have gained huge attention among the scientific community and hold great promise to limit cancer metastasis. In this study, green-derived ... -
Potent In Vitro Phosphodiesterase 1 Inhibition of Flavone Isolated from Pistacia integerrima Galls
(biomed research international, 2022)To prospect an isozyme-specific, effective inhibitor against the physiologically-crucial enzyme phosphodiesterase 1 (PDE1), phytochemicals from Pistacia integerrima galls were screened. The chloroform fraction of gall ... -
A Review of Recent Studies on the Antioxidant and Anti-Infectious Properties of Senna Plants
(oxidative medicine and cellular longevity, 2022)The use of phytochemicals is gaining interest for the treatment of metabolic syndromes over the synthetic formulation of drugs. Senna is evolving as one of the important plants which have been vastly studied for its ... -
Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
(evidence based complementary and alternative medicine, 2022)Polyalthia suberosa (Roxb.) is a plant used to cure coughs, dysentery, fevers, joint aches, rheumatic pain, inflammation, and a variety of skin diseases. *e aim of the study was to evaluate the ethyl acetate extract of ... -
Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential
(oxidative medicine and cellular longevity, 2022)Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum L.) and in wood and bark of some tree ... -
Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications
(evidence based complementary and alternative medicine, 2022)Urtica dioica belongs to the Urticaceae family and is found in many countries around the world. 1is plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, ... -
Biosynthesis of Secondary Metabolites Based on the Regulation of MicroRNAs
(biomed research international, 2022)MicroRNA (miRNA), a noncoding ribonucleic acid, is considered to be important for the progression of gene expression in plants and animals by rupture or translational repression of targeted mRNAs. Many types of miRNA ... -
Evaluation of mutagenesis, necrosis and apoptosis induced by omeprazole in stomach cells of patients with gastritis
(cancer cell international, 2022)Background: Gastritis is a superfcial and prevalent infammatory lesion that is considered a public health concern once can cause gastric ulcers and gastric cancer, especially when associated with Helicobacter pylori ... -
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives
(oxidative medicine and cellular longevity, 2022)Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of ... -
Pharmacological effects and therapeutic potential of natural compounds in neuropsychiatric disorders: An update
(Frontiers Media SA, 2022)Neuropsychiatric diseases are a group of disorders that cause significant morbidity and disability. The symptoms of psychiatric disorders include anxiety, depression, eating disorders, autism spectrum disorders (ASD), ...
