Browsing Uygulama ve Araştırma Merkezleri by Title
Now showing items 17-36 of 36
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GENETIC EROSION AND CONSERVATION GENETICS
(26.12.2023)Conservation biologists study the factors that cause species extinction/loss and which species can be protected to ensure the continuation of biodiversity. However, with the development of genetic science and its use as ... -
IN SILICO ACTIVITY PREDICTION: ADME-TOX ASSESSMENT AND MOLECULAR DYNAMICS
(18.12.2023)The way to create new drugs is to map out the hallmarks of a disease by finding small molecules that can modulate the function of known target molecules. Furthermore, there is a need to identify and obtain small molecules ... -
IN VITRO INVESTIGATION OF THE INHIBITORY EFFECT OF HEPATOTOXIC DIETHYLNITROSAMINE COMPOUND ON XANTHINE OXIDASE ENZYME
(BZT AKADEMİ YAYINEVİ, aralık 202)Aim: It was aimed to examine the inhibition effect of diethyl nitrosamine compound, one of the nitrosole compounds known to have carcinogenic and hepato-toxic effects, on xanthine oxidase enzyme in vitro. Materials-Method: ... -
Investigating the effect of ribavirin treatment on genetic mutations in Crimean-Congo haemorrhagic fever virus (CCHFV) through next-generation sequencing.
(2023)Crimean-Congo haemorrhagic fever (CCHF) is the most widespread tick-borne viral haemorrhagic fever affecting humans, and yet a licensed drug against the virus (CCHFV) is still not available. While several studies have ... -
Levels of oxidative stress and apoptosis-related biomarkers in endometriosis
(Cukurova Üniverstesi, 2023)Abstract Öz Purpose: In this study, the apoptosis marker M30, the oxidative stress markers malondialdehyde, (MDA) and asymmetric dimethyl arginine (ADMA) have been studied in the context of endometriosis. Materials ... -
MOLEKÜLER TÜR TANIMLAMASINDA BIR ARAÇ OLARAK DNA BARKODLAMA
(2022)GİRİŞ Türlerin taksonomik tanımlamasında DNA kullanma kavramı ilk olarak Hebert ve Gregory tarafından önerilmiştir (P. D. Hebert ve ark., 2003). DNA barkodlama kavramı, türleri birbirinden ayırmak için kullanılabilen ... -
MULTIOMICS: HUMAN DISEASES AND MACHINE LEARNING
(09.12.2023)Integrating different types of omics data with each other can help learn clinical-pathogenic changes that may be the cause of the disease, and these analyzes can be tested and confirmed by molecular studies in the next ... -
OMURGASIZ ANTİMİKROBİYAL PEPTİDLERİ: POTANSİYEL TERAPÖTİK UYGULAMALAR
(İKSAD YAYINEVİ, 2022)GİRİŞ Konak savunma peptidleri veya antimikrobiyal peptidler (AMP'ler), doğuştan gelen bağışıklık sisteminin en önemli anahtar bileşenlerinden biridir (Zasloff, 2002; Hancock ve ark., 2012). Enfeksiyöz ajanlara karşı ilk ... -
PSİKOFARMAKOLOJİDE KULLANILAN LİTYUM TUZLARININ GLİKOZ-6-FOSFAT DEHİDROGENAZ ENZİMİ ÜZERİNDEKİ ETKİSİ
(ISPEC, 30.07.2023)Amaç: Glikoz metabolizmasında anahtar görevi yapan ve tüm hücrelerde bulunan Glukoz-6-Fosfat Dehidrogenaz (G6PD) enzimi, özellikle pentoz fosfat yolağının (PFY) ilk adımında rol oynamaktadır. Bu yolakta hız kısıtlayıcı ... -
Removal of Erythrosine B dye from wastewater by Penicillium italicum: experimental, DFT, and molecular docking studies
(2023)The study involved the adsorption of Erythrosine B onto the dead, dry, and unmodified Penicillium italicum cells and the analytical, visual, theoretical assessment of the adsorbent-adsorbate interactions. It also included ... -
RNAi Terapötikleri: Viral Hastalıklar ve Kanser
(2023)RNA interferens (RNAi), bir gen dizisini tamamlayıcı olan ve hedeflenen dizinin spesifik susturulmasına aracılık eden, tipik olarak 19-23 nükleotidden oluşan kısa RNA dizilerinin temel prensibine dayanır (Kelleher ve ark., ... -
SINGLE-CELL MASS CYTOMETRY AND TRANSCRIPTOME PROFILING
(09.12.2023)Single-cell cytometry, a research tool, has been used for almost half a century. Flow cytometry has long been the primary method for cytometric analysis, and data processing/analysis operations have been heavily influenced ... -
SIRT1, MMP-9 and TIMP-1 levels in children with specific learning disorder
(Elsevier, 01.0.8.202)bstract Background Specific Learning Disorder (SLD) is a common developmental and neurobiological disorder of childhood characterized by impairment of functionality in one or more areas such as reading, writing, mathematics, ... -
Sivas Kent Araştırmaları Kaynakçası : Millî Mücadele ve Sivas Kongresi'nin 100. Yılı Anısına
(Sivas Cumhuriyet Üniversitesi, 2020)Osmanlı döneminde şehirlerin güzelliklerini anlatan "Şehrengiz" tarzı eserlerin yazıldığı bilinmektedir. şehrengiz geleneği, özellikle XVI. ve XVIII. yüzyıllar arası dönemde yoğun olarak sürdürülmüştür. XIX. ve ... -
SPECTROSCOPIC TEST TYPES USED IN ANTIOXIDANT CAPACITY DETERMINATION
(İksad publishing house, 31 Aralık )These days, antioxidants are an essential component of our life. Before free radicals, also known as "Reactive Oxygen Species" (ROS), may harm cells, antioxidants aid in their neutralization or destruction. This chapter ... -
SPECTROSCOPIC TRACE ELEMENT ANALYSIS IN BIOLOGICAL SAMPLES
(Liberty Academic Publishers, Aralık 202)Trace elements are inorganic components that have important functions in our body. Their levels are important for the diagnosis and treatment of various diseases in the living body, as well as detection of conditions ... -
Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection
(Proceedings of the National Academy of Sciences of the United States of America, 05.09.2023)Crimean-Congo hemorrhagic fever (CCHF) caused by CCHF virus (CCHFV) is one of the epidemic-prone diseases prioritized by the World Health Organisation as public health emergency with an urgent need for accelerated research. ... -
The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19.
(2023)Toll-like receptors (TLRs) recognize infectious agents and play an important role in the innate immune system. Studies have suggested that TLR single nucleotide polymorphisms (SNPs) are associated with poor antiviral ... -
TOOLS AND GEARS FOR METABOLOMICS ANALYSIS
(2023)Since its initiation within the late 1990s, metabolomics has made a critical advance as a profound phenotyping device. Metabolomics is displayed with expanded dimensionality (2D and 3D) and high-resolution expository stages ... -
usage of ICP-MS in biological samples
(İksad, Mart 2023)ÖZET ICP-MS olarak bilinen indüktif eşleşmiş plazma-kütle spektroskopisi, temel inorganik bileşiklerden olan eser element, mineral ve ağır metaller gibi periyodik tabloda bulunan birçok elementin analizini yüksek seçicilik ...