Evaluation of Myocardial Perfusion Imaging SPECT Parameters and Pharmacologic Stress Test with Adenosine Versus Coronary Angiography Findings: Are They Diagnostically Concordant?

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dc.contributor.authorHasbek, Zekiye
dc.contributor.authorErturk, Seyit Ahmet
dc.contributor.authorCakmakcilar, Ali
dc.contributor.authorGul, Ibrahim
dc.contributor.authorYilmaz, Ahmet
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:37:02Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:37:02Z
dc.date.issued2019
dc.department[Hasbek, Zekiye -- Erturk, Seyit Ahmet -- Cakmakcilar, Ali] Cumhuriyet Univ, Fac Med, Dept Nucl Med, Sivas, Turkey -- [Gul, Ibrahim -- Yilmaz, Ahmet] Cumhuriyet Univ, Fac Med, Dept Cardiol, Sivas, Turkeyen_US
dc.description.abstractObjectives: In this study our first aim was to evaluate the diagnostic concordance of myocardial perfusion scintigraphy (MPS) by pharmacological stress test with adenosine (APST) with coronary angiography (CAG). The secondary aim of this study was to evaluate the correlation between CAG findings and automated analysis parameters such as left ventricular ejection fraction, summed stress score (SSS), summed rest score, summed difference score (SDS), stress MPS defect percentage ratio (extent) and transient ischemic dilation (TID) obtained by myocardial perfusion imaging single-photon emission computed tomography (SPECT). Methods: A total of 129 patients (62 male, 67 female, median age: 60.02) undergoing MPS due to suspicion of coronary ischemia who also underwent subsequent CAG in the last year were included in this study, their MPS data and CAG results were compared. Results: There was no statistically significant diagnostic concordance when visual evaluation of MPS, quantitative MPS parameters and exercise treadmill test (ETT) electrocardiography results were used alone. In fact, diagnostic concordance was higher when automated analysis parameters like TID, SSS and extent values were added to MPS SPECT visual analyses. There was diagnostic concordance in 57.9% of APST patients and 41.7% of ETT patients. There was diagnostic concordance in 75.8% of APST patients and 52.6% of ETT patients who were older than 65 years of age. Conclusion: In our study, we found that the use of APST during MPS increases diagnostic concordance with CAG. Therefore, we think that it would be appropriate to use APST in women and elderly patients with limited exercise habits. The CAG diagnostic mismatch is far above what it should be when MPS reporting is only done with visual data, and it is not supported by quantitative data such as TID, SSS, SDS and extent.en_US
dc.identifier.doi10.4274/mirt.2019.47450en_US
dc.identifier.endpage61en_US
dc.identifier.issn2146-1414
dc.identifier.issn2147-1959
dc.identifier.issue2en_US
dc.identifier.pmid31237135en_US
dc.identifier.scopus2-s2.0-85070746883en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage53en_US
dc.identifier.trdizinid368595en_US
dc.identifier.urihttps://dx.doi.org/10.4274/mirt.2019.47450
dc.identifier.urihttps://hdl.handle.net/20.500.12418/5884
dc.identifier.volume28en_US
dc.identifier.wosWOS:000472637800002en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofMOLECULAR IMAGING AND RADIONUCLIDE THERAPYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyocardial perfusionen_US
dc.subjectSPECTen_US
dc.subjectadenosineen_US
dc.subjectstress testen_US
dc.subjectquantitative parametersen_US
dc.titleEvaluation of Myocardial Perfusion Imaging SPECT Parameters and Pharmacologic Stress Test with Adenosine Versus Coronary Angiography Findings: Are They Diagnostically Concordant?en_US
dc.typeArticleen_US

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