Risk of autism spectrum disorder in children with a history of hospitalization for neonatal jaundice

Basit Öğe Kaydı
dc.authoridKilicbay, Fatih/0000-0001-9073-0864
dc.authoridUzun Cicek, Ayla/0000-0003-2274-3457
dc.authoridTunc, Gaffari/0000-0001-7837-3948
dc.contributor.authorTunc, Gaffari
dc.contributor.authorUzun Cicek, Ayla
dc.contributor.authorKilicbay, Fatih
dc.date.accessioned2024-10-26T18:00:21Z
dc.date.available2024-10-26T18:00:21Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground/aim: Limited research has focused explicitly on the association between neonatal jaundice and autism spectrum disorder (ASD), and inconclusive evidence exists in the literature within this framework. This study aimed specifically to investigate whether neonatal jaundice is a potential risk factor for ASD and whether there is a connection between the types of neonatal jaundice and the severity of ASD. Materials and method: This study involved 119 children with ASD [90 males (75.6%), 29 females (24.4%), mean age: 45.39 +/- 11.29 months] and 133 healthy controls [100 males (75.2%), 33 females (24.8%), mean age: 46.92 +/- 11.42 months]. Psychiatric disorders were diagnosed through the Diagnostic and Statistical Manual of Mental Disorders criteria. Childhood Autism Rating Scale (CARS) was used to assess the screening and diagnosis of autism. A specially prepared personal information sheet was employed to investigate sociodemographic characteristics and birth and clinical histories. Results: The rate of the history of jaundice and pathological jaundice requiring hospitalization and phototherapy were significantly higher in the ASD group compared to the controls. CARS total score and the mean scores of nearly all items were statistically higher in children with a history of pathological jaundice than those with a history of physiological jaundice. Conclusion: Neonatal jaundice, depends on its severity, seems to be one of the possible biological factors associated with subsequent development of and the severity of ASD. Establishing a causal relationship between neonatal jaundice and ASD by more comprehensive studies may contribute to alleviating of the severity of ASD for individuals at risk.
dc.identifier.doi10.3906/sag-2103-263
dc.identifier.endpage2665
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5
dc.identifier.pmid34344142
dc.identifier.scopus2-s2.0-85120799169
dc.identifier.scopusqualityQ3
dc.identifier.startpage2657
dc.identifier.trdizinid479543
dc.identifier.urihttps://doi.org/10.3906/sag-2103-263
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/479543
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27651
dc.identifier.volume51
dc.identifier.wosWOS:000711339600050
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNewborn
dc.subjectautism spectrum disorder
dc.subjectneonatal jaundice
dc.subjectphototherapy
dc.titleRisk of autism spectrum disorder in children with a history of hospitalization for neonatal jaundice
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu