Familial Mediterranean fever: Health-related quality of life and associated variables in a national cohort

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dc.authoridNAS, Kemal/0000-0002-5845-0851
dc.authoridUcar, Ulku/0000-0003-4838-1650
dc.authoridSen, Nesrin/0000-0003-0966-0075
dc.authoridYurdakul, Ozan Volkan/0000-0003-4567-8133
dc.authoridDuruoz, Mehmet Tuncay/0000-0003-3584-2788
dc.authoriddemir, ali nail/0000-0001-5713-4120
dc.authoridkarahan, ali yavuz/0000-0001-8142-913X
dc.contributor.authorBodur, Hatice
dc.contributor.authorYurdakul, Fatma Gul
dc.contributor.authorDuruoz, Mehmet Tuncay
dc.contributor.authorCay, Hasan Fatih
dc.contributor.authorUcar, Ulku
dc.contributor.authorKeskin, Yasar
dc.contributor.authorSargin, Betul
dc.date.accessioned2024-10-26T18:00:18Z
dc.date.available2024-10-26T18:00:18Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: This study aims to evaluate the effectivity of Familial Mediterranean Fever Quality of Life (FMF-QoL) Scale for the measurement of QoL in patients with FMF and to perform correlations between related clinical variables in Turkish patients. Patients and methods: This multicenter prospective study performed between December 2017 and November 2018 included 974 FMF patients (334 males, 640 females; median age: 35; range, 26 to 45 years). Sociodemographic characteristics and clinical features were recorded. All participants were asked to complete the FMF-QoL Scale, Short Form-36 (SF-36), Hospital Anxiety and Depression Scale (HADS), Health Assessment Questionnaire (HAQ), and Functional Assessment of Chronic Illness Therapy (FACIT) Scale. Results: The median FMF-QoL Scale score was 26. Higher FMF-QoL Scale scores were shown to be related to female sex, illiteracy or primary education, monthly low-income (US$<300), smoking, late-onset FMF (>20 years), a higher number of attacks per month (>1/month), and severe disease. FMF-QoL Scale scores were correlated negatively with subscales of SF-36, and positively with HADS-anxiety and HADS-depression scores, HAQ and FACIT. Conclusion: Female sex, smoking, lower educational status, more severe disease, fatigue, and functional impairment were associated with poor QoL. FMF-QoL Scale was noted as a valid and simple patient-reported outcome instrument and correlated with the SF-36 scale.
dc.identifier.doi10.46497/ArchRheumatol.2021.8215
dc.identifier.endpage166
dc.identifier.issn2148-5046
dc.identifier.issn1309-0283
dc.identifier.issue2
dc.identifier.pmid34527919
dc.identifier.scopus2-s2.0-85107826111
dc.identifier.scopusqualityQ4
dc.identifier.startpage159
dc.identifier.trdizinid445721
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2021.8215
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/445721
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27626
dc.identifier.volume36
dc.identifier.wosWOS:000657513700001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish League Against Rheumatism
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAutoinflammatory diseases
dc.subjectdepression
dc.subjectfatigue
dc.subjecthereditary
dc.subjectlife quality
dc.titleFamilial Mediterranean fever: Health-related quality of life and associated variables in a national cohort
dc.typeArticle

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