Ethnomedicinal Use, Phytochemistry, and Pharmacology of Xylocarpus granatum J. Koenig

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dc.authorid0000-0003-4946-5602tr
dc.contributor.authorDurna Daştan, Sevgi
dc.contributor.authorDey, dipta
dc.contributor.authorQuispe, christina
dc.contributor.authorhossain, rajib
dc.contributor.authorjain, divya
dc.contributor.authorKhan, rasel Ahmed
dc.contributor.authorJanmeda, Pracheta
dc.contributor.authorIslam, Muhammed toregul
dc.contributor.authorSuleria, hafız ansar Rasul
dc.contributor.authorMorterell, Miguell
dc.contributor.authorKumar, Manoj
dc.contributor.authortahari, yasaman
dc.contributor.authorPetkovska, anka trajkovska
dc.contributor.authorRad, Javad sharifi
dc.date.accessioned2022-05-13T13:14:39Z
dc.date.available2022-05-13T13:14:39Z
dc.date.issued2021tr
dc.departmentFen Fakültesitr
dc.description.abstract.e mangrove plants are the potential sources of foods and remedies for people living in the forests and nearby communities. Xylocarpus granatum J. Koenig is traditionally used to treat various diseases including diarrhea, cholera, dysentery, fever, malaria, and viral infections, among others. To summarize critically the taxonomy, ethnomedicinal, phytochemistry, and pharmacological activities of X. granatum, information was collected from different databases. An up-to-date search (till June 2020) was carried out with the help of various scientific web resources from databases such as PubMed, Science Direct, Google Scholar, and various patent offices (e.g., WIPO, CIPO, and USPTO) using the keywords “Xylocarpus granatum” and then paired with ethnomedicinal use and phytochemical, phytochemistry, and pharmacological activity (in vitro, ex vivo, and in vivo studies). Findings revealed that seeds, fruits, stem bark, leaf, and twigs of X. granatum exhibited a wide range of key phytochemicals including limonoids, phragmalin, limonoid-based alkaloids, mexicanolides, protolimonoids, flavonols, and lactones. .e plant possessed potent antioxidant, anticancer, antidiabetic, antimicrobial, antimalarial, antifeedant, and neuroprotective activities. No clinical studies have been reported in the databases. Ethnomedicinal assessment indicated the application of X. granatum in various fields of medical science specially to treat various human ailments, and this was attributed to the presence of enormous alkaloids as confirmed by pharmacological studies. However, to understand the mechanism of action in-depth studies are required. In view of these findings, more research is necessary to explore and characterize the chemical compounds and toxicological aspects of this medicinal mangrove plant. Overall, it can be stated that X. granatum may be one of the hopeful medicinal herbs for the treatment of various diseases in human beings.tr
dc.identifier.doi10.1155/2021/8922196en_US
dc.identifier.pmid34504541en_US
dc.identifier.scopus2-s2.0-85115346943en_US
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://hdl.handle.net/20.500.12418/13097
dc.identifier.wosWOS:000695477500008en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofEvidence-Based Complementary and Alternative Medicineen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıtr
dc.rightsinfo:eu-repo/semantics/closedAccesstr
dc.titleEthnomedicinal Use, Phytochemistry, and Pharmacology of Xylocarpus granatum J. Koenigen_US
dc.typeArticleen_US

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