Evaluation of organic load-related efficacy changes in antiseptic solutions used in hospitals

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dc.authoridHalat, Ece/0000-0003-1269-7944
dc.authoridSahiner, Asli/0000-0001-5095-9461
dc.contributor.authorSahiner, Asli
dc.contributor.authorHalat, Ece
dc.contributor.authorAlgin Yapar, Evren
dc.contributor.authorKara, Bilge Ahsen
dc.date.accessioned2024-10-26T18:00:31Z
dc.date.available2024-10-26T18:00:31Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground/aim: In this study, it was aimed to evaluate the change in antimicrobial efficacy related to the presence of the organic load of four different antiseptic solutions that are frequently used in hospitals. Materials and methods: Solutions of hydrogen peroxide, povidone-iodine, chlorhexidine digluconate, and ethyl alcohol were prepared, tested in terms of antimicrobial efficacy changes in the presence of organic substances, and evaluated according to EN 13727 and EN 13624 standards. Results: Among the investigated solutions ethanol 70% solution showed the best results by providing a 5-log reduction on all test organisms without affecting by the type and concentration of organic substances. Solutions of hydrogen peroxide 3%, povidone-iodine 7.5%, and chlorhexidine digluconate 0.2% performed lower antimicrobial efficacy depending on the concentration of organic load. Conclusion: It is concluded that the antimicrobial efficacy of antiseptic solutions is significantly affected by the organic substances and thus the proper use of antiseptics has become important to achieve successful disinfection and prevention of antibacterial resistance.
dc.identifier.doi10.55730/1300-0144.5379
dc.identifier.endpage833
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue3
dc.identifier.pmid36326304
dc.identifier.scopus2-s2.0-85133127032
dc.identifier.scopusqualityQ3
dc.identifier.startpage825
dc.identifier.trdizinid536643
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5379
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/536643
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27735
dc.identifier.volume52
dc.identifier.wosWOS:000816957200037
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntiseptic solutions
dc.subjectorganic load in hospitals
dc.subjectantimicrobial efficacy
dc.subjectEN 13727
dc.subjectEN 13624
dc.titleEvaluation of organic load-related efficacy changes in antiseptic solutions used in hospitals
dc.typeArticle

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