Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkey

Basit Öğe Kaydı
dc.contributor.authorHeydari, Hajar
dc.contributor.authorIscan, Gulcin Saltan
dc.contributor.authorEryilmaz, Mujde
dc.contributor.authorAcikara, Ozlem Bahadir
dc.contributor.authorSarialtin, Sezen Yilmaz
dc.contributor.authorTekin, Mehmet
dc.contributor.authorCoban, Tulay
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:37:04Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:37:04Z
dc.date.issued2019
dc.department[Heydari, Hajar -- Iscan, Gulcin Saltan -- Acikara, Ozlem Bahadir] Ankara Univ, Fac Pharm, Dept Pharmacognosy, Ankara, Turkey -- [Eryilmaz, Mujde] Ankara Univ, Fac Pharm, Dept Pharmaceut Microbiol, Ankara, Turkey -- [Sarialtin, Sezen Yilmaz -- Coban, Tulay] Ankara Univ, Fac Pharm, Dept Pharmaceut Toxicol, Ankara, Turkey -- [Tekin, Mehmet] Cumhuriyet Univ, Fac Pharm, Dept Pharmaceut Bot, Sivas, Turkeyen_US
dc.description.abstractObjectives: The present study aimed to evaluate the antimicrobial and anti-inflammatory activities of methanol extracts and n-hexane, ethyl acetate, chloroform, and water fractions of five Lathyrus species, namely Lathyrus armenus, Lathyrus aureus, Lathyrus cilicicus, Lathyrus laxiflorus subsp. laxiflorus, and Lathyrus pratensis, growing in Turkey. Materials and Methods: The antimicrobial activities were screened against Staphylococcus aureus ATCC 29213, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Candida albicans ATCC 10231. Broth dilution was used to determine the antimicrobial activities of extracts and fractions. In vitro anti-inflammatory activity of these extracts and fractions was determined using human red blood cell membrane stabilization. Results: The results demonstrated that ethyl acetate fractions of the tested species exhibited higher antimicrobial activity than the other extracts. Among all of the tested extracts and fractions, the highest anti-inflammatory activity was detected in water fractions. Furthermore, water fractions of L. pratensis showed better anti-inflammatory activity than acetylsalicylic acid and diclofenac sodium, which were used as standard drugs in this assay. Conclusion: The results indicate the membrane stabilizing effect of the various extracts and fractions of the Lathyrus species and could constitute preliminary work for in vivo anti-inflammatory activity experiments.en_US
dc.identifier.doi10.4274/tjps.galenos.2018.86719en_US
dc.identifier.endpage245en_US
dc.identifier.issn1304-530X
dc.identifier.issue2en_US
dc.identifier.pmid32454720en_US
dc.identifier.scopus2-s2.0-85065676193en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage240en_US
dc.identifier.trdizinid354202en_US
dc.identifier.urihttps://dx.doi.org/10.4274/tjps.galenos.2018.86719
dc.identifier.urihttps://hdl.handle.net/20.500.12418/5900
dc.identifier.volume16en_US
dc.identifier.wosWOS:000462991400016en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTURKISH PHARMACISTS ASSOCen_US
dc.relation.ispartofTURKISH JOURNAL OF PHARMACEUTICAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-inflammatory activityen_US
dc.subjectantimicrobial activityen_US
dc.subjecthuman red blood cell membraneen_US
dc.subjectLathyrusen_US
dc.titleAntimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu