Association Between Familial Mediterranean Fever and Cachexia in Females

Basit Öğe Kaydı
dc.authoridilhanli, ilker/0000-0002-7998-8992
dc.authoridcengiz, ahmet kivanc/0000-0002-4390-7169
dc.authoridDurmaz, Yunus/0000-0002-1727-0088
dc.authoridHASBEK, Zekiye/0000-0002-8119-3363
dc.contributor.authorDurmaz, Yunus
dc.contributor.authorIlhanli, Ilker
dc.contributor.authorCengiz, Ahmet Kivanc
dc.contributor.authorKaptanoglu, Ece
dc.contributor.authorOzkan Hasbek, Zekiye
dc.contributor.authorHizmetli, Sami
dc.date.accessioned2024-10-26T18:00:20Z
dc.date.available2024-10-26T18:00:20Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: This study aims to investigate the association between familial Mediterranean fever (FMF) and cachexia in females. Patients and methods: The study included 32 female FMF patients (median age 27.50 years; range, 18 to 50 years) and 30 female healthy controls (median age 32 years; range, 18 to 50 years). Patients were classified according to Tel-Hashomer criteria. Circumference of arm, waist, and thigh was recorded. Short form 36 (SF-36) and Multidimensional Assessment of Fatigue (MAF) scale were applied. Composition of the body was measured with dual X-ray absorption. Muscle strength was measured with an isokinetic dynamometer, and strength of hand grip was measured from dominant hand with a hand dynamometer. C-reactive protein, erythrocyte sedimentation rate, fibrinogen and serum creatinine kinase (CK) levels were recorded. Results: Body mass index was significantly higher in controls. Twelve patients and one control had cachexia. CK level was significantly higher in patients than controls. Mass of muscle without fat was significantly higher in patients than controls. Peak torque values of extension and flexion at the velocity of 60 degrees/second [Newton meter (Nm)], and value of total work during extension at the velocity of 240 degrees/second (Nm) in isokinetic measures were significantly higher in controls. MAF score was significantly higher in patients with cachexia than patients without cachexia where the subscale scores of SF-36, except the vitality score, were significantly lower in patients with cachexia. However, Tel-Hashomer score was significantly higher in patients with cachexia. Conclusion: This study pointed at a significant association between cachexia and FMF in females. Muscle endurance was not affected in FMF patients with cachexia; however, decreased muscle strength, impaired quality of life and increased fatigue were observed in these patients.
dc.identifier.doi10.46497/ArchRheumatol.2020.7632
dc.identifier.endpage485
dc.identifier.issn2148-5046
dc.identifier.issn1309-0283
dc.identifier.issue4
dc.identifier.pmid33758804
dc.identifier.scopus2-s2.0-85097810928
dc.identifier.scopusqualityQ4
dc.identifier.startpage477
dc.identifier.trdizinid457531
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2020.7632
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/457531
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27641
dc.identifier.volume35
dc.identifier.wosWOS:000595829400003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish League Against Rheumatism
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCachexia
dc.subjectfamilial Mediterranean fever
dc.subjectfatigue
dc.subjectmuscle strength
dc.subjectquality of life
dc.titleAssociation Between Familial Mediterranean Fever and Cachexia in Females
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu