Evaluation of Serum Amyloid A and Procalcitonin in Some Inflammatory Diseases of Cattle

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dc.contributor.authorBasbug, Onur
dc.contributor.authorYurdakul, Ibrahim
dc.contributor.authorYuksel, Murat
dc.date.accessioned2024-10-26T18:00:15Z
dc.date.available2024-10-26T18:00:15Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractRecent study in humans and animals has been focused on inflammatory biomarkers that infectious diseases, such as serum amyloid A (SAA), procalcitonin (PCT), that may more accurately and efficiently diagnose inflammation. The aim of this study was to evaluate SAA and PCT levels in the diagnosis of cattle with inflammatory disease. Ten healthy control cattle and 64 patients with systemic inflammatory response syndrome (SIRS) were included in cattle. Inflammatory disease in cattle was diagnosed based on clinical signs and the laboratory examination in clinically suspected cases. SAA and PCT concentrations were measured with a commercial ELISA assay for cattle. SAA and PCT concentrations in cattle with inflammatory disease were significantly higher than in the healthy controls (respectively, P<0.001, P<0.008). Concentrations of SAA and PCT at admission were significantly (r = 0.376, P<0.01) correlated with outcome in cattle with inflammatory conditions. The cut-off value of SAA and PCT for healthy and inflammatory cattle was determined 28.52 mu g/mL and 149.55 pg/mL. In conclusion, PCT levels may be used as an alternative to serum SAA measurement as an indicator of acute inflammation in cattle. Serum PCT concentrations were similar to 9 times higher in the cattle with peritonitis than in the healthy cattle, suggesting that PCT could be a useful marker of peritonitis in cattle.
dc.identifier.doi10.9775/kvfd.2019.23412
dc.identifier.endpage402
dc.identifier.issn1300-6045
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85081237800
dc.identifier.scopusqualityQ3
dc.identifier.startpage397
dc.identifier.trdizinid382200
dc.identifier.urihttps://doi.org/10.9775/kvfd.2019.23412
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/382200
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27572
dc.identifier.volume26
dc.identifier.wosWOS:000519111600013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisi
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCattle
dc.subjectMarker
dc.subjectProcalcitonin
dc.subjectSerum amyloid A
dc.titleEvaluation of Serum Amyloid A and Procalcitonin in Some Inflammatory Diseases of Cattle
dc.typeArticle

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