Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study

dc.contributor.authorIpek, Irem
dc.contributor.authorUnal, Murat
dc.contributor.authorKoc, Tulay
dc.date.accessioned2024-10-26T18:07:59Z
dc.date.available2024-10-26T18:07:59Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources (Elipar S10 and Valo ) [Group 1: Kalore Elipar S10 (KE), Group 2: Kalore Valo (KV), Group 3: Essentia Elipar S10 (EE), Group 4: Essentia Valo (EV)] were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes [Group 5: (Control group)] were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals (n=8). Biopsy samples were stained with H&E and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines (IL-1 beta, IL-6 and IL-8). Results When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.
dc.description.sponsorshipSivas Cumhuriyet University Scientific Research Projects (CUBAP) [DIS-246]
dc.description.sponsorshipFinancial Disclosure: The present study was supported by Sivas Cumhuriyet University Scientific Research Projects (CUBAP) (Project number: DIS-246) .
dc.identifier.doi10.26650/eor.20231260787
dc.identifier.endpage29
dc.identifier.issn2630-6158
dc.identifier.issn2651-2823
dc.identifier.issue1
dc.identifier.pmid38481718
dc.identifier.scopus2-s2.0-85183676244
dc.identifier.scopusqualityQ3
dc.identifier.startpage22
dc.identifier.trdizinid1277218
dc.identifier.urihttps://doi.org/10.26650/eor.20231260787
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29757
dc.identifier.volume58
dc.identifier.wosWOS:001148640700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherIstanbul Univ Press, Istanbul Univ Rectorate
dc.relation.ispartofEuropean Oral Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCompositeresins
dc.subjectlightsources
dc.subjectbiocompatibility
dc.subjectrat
dc.subjectimmunohistochemistry
dc.titleBiocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study
dc.typeArticle

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