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Now showing items 481-490 of 517
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)
The combination of a commercially available PGLA
(poly[glycolide-co-L-lactide]), 90:10% suture material with bio active bioglass nanopowders (BGNs) and graphene oxide (GO)-
doped BGNs offers new opportunities for the ...
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)
Background:
Fibromyalgia is a soft tissue rheumatism characterized by chronic and
widespread musculoskeletal pain at specific points in the body.
Objectives:
In this study, we aimed to investigate the relationship ...
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 05.09.2023)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed compound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ...
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(2023)
Mushrooms, which have been collected to meet the nutritional needs of the world for many years,
have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies
carried out to determine ...
Machine Learning Approaches for One-Day Ahead Soil Temperature Forecasting
(2023)
Present study investigates the capabilities of six distinct machine learning techniques such as ANFIS network with fuzzy c-means (ANFIS-FCM), grid partition (ANFIS-GP), subtractive clustering (ANFIS-SC), feed-forward neural ...
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
(2023)
The cytotoxic activities of the compounds were determined by the 3‐(4,
5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human
breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
(2023)
Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse
model.
Materials and Methods: Five groups were formed with eight ...
Chemical and functional composition and biological activities of Anatolian Hypericum scabrum L. plant
(2023)
Hypericum scabrum L. plant has wide use in ethnopharmacology and is cultivated both naturally and technologically. This study was conducted to determine chemical and functional properties and in vitro biological activities ...
New Fluoro- and Trifluoromethyl-Substituted Trimethoxychalcones as Anticancer Agents: Synthesis, Bioevaluation, and Computational Studies
(2023)
We designed and synthesized a novel series of trimethoxy
chalcones with CF3 or F substituents at various positions of ring
B, characterized using IR, NMR spectral data, and elemental
analyses, based on the fact that ...