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Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies
(2021)
In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyano phenoxy)phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted
metallophthalocyanines ...
Michael/Michael Addition Cascade of 2-Benzylidene-1- indanones with Chalcones: Synthesis and Biological Evaluations of Novel Polycyclic Compounds
(2021)
A series of novel racemic 2-aryloyl-1,3-diaryl-2,3,3a,8a-tetrahy drocyclopenta[a]inden-8(1H)-one derivatives were synthesized
from KOtBu mediated Michael/Michael addition reaction of 2-
benzylidene-1-indanones with ...
Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects
(2021)
: In this study, 12 new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives
were designed and synthesized to investigate their cytotoxic effects. The in vitro cytotoxic activities
of the compounds were ...
Selective cytotoxicity of paclitaxel bonded silver nanoparticle on different cancer cells
(2021)
Paclitaxel (PTX) is one of the most effective drugs in the treatment of cancer. However, its usability is limited due
to low solubility and side effects. In this study, we investigated anticancer effects of PTX bonded ...