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Possible effects of clinoptilolite on small intestinal ischemia-reperfusion injury caused by experimental mesenteric artery occlusion
(2022)
Objectives: Mesenteric ischemia is a surgical emergency caused by poor blood supply to the intestines. In ischemia,the decrease in blood flow to the tissue causes acidosis and cell death through anaerobic metabolism. ...
Design, synthesis and in vitro antiproliferation activity of some 2-aryl and -heteroaryl benzoxazole derivatives
(2022)
Background: Phortress produces reactive electrophilic metabolites that form DNA adducts only in
sensitive tumor cells. The authors converted the 2-phenylbenzothiazole nucleus in phortress to 2-
aryl and -heteroaryl ...
Poli[Maleik Anhidrit-Ko-Vinil Asetat] Kopolimerinin Doksorubisin/Doksorubisin Türevi Antikanser İlaçlarla Doğrusal Rasyonel Konjugatlarının Sentezi, Yapısal Karakterizasyonları Ve Çeşitli Kanser Hücreleri Üzerinde Sitotoksik/Antikanser Aktiviteleri
(20.01.2022)
Nanotoksik özellikli poli[Maleik Anhidrit-Ko-Vinil Asetat] kopolimerinin sentezlenmesinden sonra ilaçlar tr için iyi bir taşıyıcı olduğu çeşitli deneysel veri ve analizlerle kanıtlanmıştır. Doksorubisin/Doksorubisin
türevi ...
circRNAs in drug resistance of breast cancer
(2022)
Abstract: Breast cancer (BC) is the most common heterogeneous disease in women and one of the leading causes of cancer-related death. Surgery, chemotherapy, radiotherapy, hormone, and targeted therapy are the gold standards ...
Synthesis, Biological Evaluation and In Silico Studies of Some 2‐Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
(2022)
In an attempt to develop potent and selective anticancer agents, some 5- or 6- and N-substituted benzoxazol-2-carbox amide derivatives were designed, synthesized, and evaluated for their cyclooxygenase inhibitory, antioxidant, ...
BİYOLOJİK VERİTABANLARI KULLANILARAK BAKTERİYEL TOPOİZOMERAZ I HEDEFLİ TERAPÖTİK DNA APTAMERİ GELİŞTİRİLMESİ
(TÜSEB, 16.05.2023)
DNA topoizomerazlar DNA topolojisini değiştirerek replikasyon ve transkripsiyon gibi canlılığı doğrudan ilgilendiren metabolik olaylarda görev alırlar. Bu nedenle kontrolsüz hücre bölünmesi/kanser ve patojenler ile savaşta ...
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(HAZİRAN 20)
ABSTRACT: Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have
gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to ...
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
(EYLÜL 2023)
Abstract: Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene]
silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1-
methallyl-3-(3,4,5 ...
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(Ekim 2023)
In this study aimed to the synthesis of novel bis-nicotinonitrile derivatives starting from 1,3-bis-chalcones and investigate their antimicrobial activity potentials. Bis-nicotinonitrile derivatives were synthesized from ...
Propolis nanoparticles synthesis and characterization with cytotoxic and apoptotic effects on breast cancer cells
(2023)
The aim of this work was to investigate the antiproliferative and pro-apoptotic effects of propolis
on human breast cancer cells using a simple and inexpensive nanoformulation. Various meth ods were used to characterize ...