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Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
(Ekim 2023)
AbstractHydrogels are three-dimensional structures with specific features that render them useful for biomedical applications, such as tissue engineering scaffolds, drug delivery systems, and wound dressings. In recent ...
Comparison of Chemical Profiles of Aronia melanocarpa Fruit Extracts
(Şubat 2023)
The chokeberry plant, which is native to North America and the south of Canada, is a deciduous, shrub-shaped, berry-like plant belonging to the Rosaceae family, which survives for many years. It is seen as a plant that ...
Imidazole‐hydrazone derivatives: Synthesis, characterization, X‐ray structures and evaluation of anticancer and carbonic anhydrase I–II inhibition properties
(19.06.2023)
The nine new imidazole-hydrazone derivatives of Schiff base
were synthesized from the condensation reactions of 1-methyl1H-imidazole-2-carbaldehyde
with various substitutedhydrazide
derivatives. Structures of the final ...
Design, synthesis, and molecular docking studies of benzimidazole‐1,3,4‐triazole hybrids as carbonic anhydrase I and II inhibitors
(30.08.2023)
In this study, with an aim to develop novel heterocyclic hybrids as potent enzyme
inhibitors, we synthesized a series of 10 novel 2- (4- (4- ethyl- 5- (2- (substitutedph
enyl)- 2- oxo- ethylthio)- 4H- 1,2,4- triazol- 3- ...
Phenolic content, antioxidant and antimicrobial activities evaluation and relationship of commercial spices in the lebanese market
(Kasım 2023)
AbstractLebanese cuisine is renowned for its distinctive flavours and vibrant aromas. In Lebanese cuisine, spices are not just used for their flavour; they are also valued for their medicinal properties. This study consists ...
Synthesis and Molecular Docking of New N-Acyl Hydrazones- Benzimidazole as hCA I and II Inhibitors
(20.01.2023)
Background: The carbonic anhydrases (CAs) which are found in most living organisms is a member of the zinc-containing metalloenzyme family. The abnormal levels and activities are frequently associated with various diseases ...
Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
(07.01.2023)
A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their
antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC
22019) and ...
Synthesis, biological evaluation and in silico studies of novel thiadiazole-hydrazone derivatives for carbonic anhydrase inhibitory and anticancer activities
(04.08.2023)
ABSTRACT
Thiadiazole and hydrazone derivatives (5a–5i) were synthesized
and their chemical structures were verified and described by
1
H NMR,
13
C NMR, and HRMS spectra. Three cancer cell lines
(MCF-7, MDA, and ...
Use of newly synthetized magnetic Fe3O4 nanoparticles modified with hexadecyl trimethyl ammonium bromide for the sensitive analysis of antidepressant drugs, duloxetine and vilazodone in wastewater and urine samples
(2023)
A new enrichment and determination method involving HPLC-DAD analysis following magnetic solidphase
extraction (MSPE) was developed to detect trace amounts of two antidepressant drugs, namely,
duloxetine (DUL) and ...
New benzimidazole‐oxadiazole derivatives: Synthesis, α‐glucosidase, α‐amylase activity, and molecular modeling studies as potential antidiabetic agents
(23.01.2023)
Benzimidazole‐1,3,4‐oxadiazole derivatives (5a–z) were synthesized and characterized
with different spectroscopic techniques such as
1
HNMR,
13
CNMR,andHRMS.The
synthesized analogs were examined against α‐glucosidase ...