Browsing Klinik Öncesi Bilimleri Bölümü by Access Type "info:eu-repo/semantics/openAccess"
Now showing items 41-59 of 59
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Parthenolide as a potential analgesic in the treatment of paclitaxel‑induced neuropathic pain: the rat modeling
(Haziran 20)In this study, we determined the therapeutic efect of parthenolide (PTL), the active component of Tanacetum parthenium, on neuropathic pain caused by paclitaxel (PTX), a chemotherapeutic drug frequently used in cancer ... -
Pharmacokinetics of meloxicam following intravenous administration at different doses in sheep
(13/09/2023)The aim of this study is to determine the pharmacokinetic change after intravenous administration of meloxicam at doses of 0.5, 1 and 2 mg/kg to sheep. The study was carried out on six Akkaraman sheep. Meloxicam was ... -
Phenolic profile and investigation of biological activities of Allium scorodoprasum L. subsp. rotundum
(06/01/2022)In this study, phenolic profile of Allium scorodoprasum L. subsp. rotundum and its bioactivity in multiway approach including antioxidant, antimicrobial, antidiabetic, cytotoxic and antiinflamatory activities were investigated. ... -
Pomegranate peel extract, N-Acetylcysteine and their combination with Ornipural alleviate Cadmium-induced toxicity in rats
(26/07/2023)Cadmium is a major environmental pollutant and a highly toxic metal. It was aimed to determine the effects of pomegranate peel extract (PPE), N-acetylcysteine (NAC) alone and along with Ornipural on cadmium-induced ... -
Prevalence of Shiga Toxin-Producing O157 and Non-O157 Escherichia coli in Anatolian Buffaloes
(Israel Journal of Veterinary Medicine, 2023)Shiga toxin producing Escherichia coli (STEC) serotypes are recognized as potentially important food-borne pathogens for humans. Ingestion of E. coli contaminated food is largely known to originate from livestock. Cattle ... -
Protective Eff ect of Melatonin and Mycophenolate Mofetil Against Nephrotoxicity Induced by Tacrolimus in Wistar Rats
(Ocak 2022)Although Tacrolimus (TAC) is a potent and well-tolerated drug, it has some side eff ects. Melatonin and mycophenolate mofetil (MMF) have some protective properties against drug-induced damage. We aimed to evaluate TAC-induced ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
(05/05/2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
(20.02.2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Roles of apoptosis and autophagy in natural rabies infections
(Ocak 2022)The aim of this study was to investigate the activity of apoptosis and autophagy in animals (cows, horses, donkeys, dogs and cats) naturally infected with rabies by using immunohistochemistry, immunofluorescence, and ... -
Synthesis of diaryl urea derivatives and evaluation of their antiproliferative activities in colon adenocarcinoma
(Nisan 2022)Colon cancer is one of the leading causes of cancer-related deaths today. Serious research for ideal chemotherapy continues today. In this context, newly synthesized molecules have an essential role in cancer treatment ... -
Synthesis, in silico and investigation of anti-breast cancer activity of new diphenyl urea derivatives: Experimental and computational study
(Ekim 2022)Cancer is a complex disease that requires multidisciplinary treatment. One of the most common cancers is breast cancer, and these cancers are usually estrogen receptor-positive. Today, chemotherapy, as well as surgery, ... -
Sığır Theileriosisi (Teşhis, Tedavi, Kontrol Stratejileri)
(Sivas Cumhuriyet Üniversitesi Rektörlük, 2022)Neospora caninum sığırlarda abortlara neden olan önemli protozoon patojenlerdendir. Etkenin son konağı köpek ve yabani kanideler, ara konakları sığır, koyun, keçi ve manda gibi sıcakkanlı hayvanlardır. Parazit ergin ... -
Şap Hastalığı
(Foot and Mouth Disease, 2022)Şap hastalığı çiftlik hayvanlarının bulaşıcı, maddi kayıplara yol açan ve 500 yıla yakın geçmişe sahip, viral bir hastalığıdır. Hastalığa ait 5 tip ülkemizde görülmüş ve canlı – cansız pek çok vektörle bulaşım olabileceği ... -
The detection and phylogenetic analysis of Anaplasma phagocytophilum-like 1, A. ovis and A. capra in sheep: A. capra divides into two genogroups.
(2022)In this study, the presence, prevalence, and genotypes of Anaplasma phagocytophilum, A. ovis, and A. capra in sheep were investigated based on 16 S SSU rRNA, groEL, and gtlA gene-specific polymerase chain reaction (PCR), ... -
The effects of low‑level laser therapy on polycystic ovarian syndrome in rats: three diferent dosages
(Ağustos 20)The main objective of this in vivo study was to investigate the efect of diferent low-level laser therapy (LLLT) doses on polycystic ovary syndrome (PCOS). In the present experimental study, a single dosage of estradiol ... -
The effects of sorafenib in healthy and cisplatin-treated rats
(07.10.2023)Background. Sorafenib is a multikinase inhibitor currently used in the treatment of hepatocellular carcinoma, renal cell carcinoma and thyroid cancer. Objectives. The literature on this agent is scarce. This study aimed ... -
The Effects of Sunitinib in Healthy and Cisplatin-Induced Rats
(04.01.2023)Sunitinib is a multitargeted kinase inhibitor that inhibits many receptor tyrosine kinases and has been used in the treatment of gastrointestinal stromal tumors, metastatic renal cell carcinoma, and pancreatic neuroendocrine ... -
The first molecular detection of Anaplasma capra in domestic ruminants in the central part of Turkey, with genetic diversity and genotyping of Anaplasma capra.
(2022)Tick-borne diseases have been an increasing threat to human and animal health all over the world. Anaplasmosis, is one of the emerging-tick borne diseases, has zoonotic potential. A new novel species, which was detected ... -
The First Molecular Detection of Two Gyroviruses (Chicken Anemia Virus and Gyrovirus galga 1) from Domestic Cats in Turkey
(17.03.2022)Gyroviruses are one of 31 genera in the family Anelloviridae. The prototype of the gyrovirus genus is Chicken anemia virus (CAV). There are 9 other species in this genus besides CAV. Gyroviruses are small, single- stranded ...