Browsing Araştırma Çıktıları | WoS by Author "Bagci, Binnur"
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Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease
Yilmaz, Meral; Sari, Ismail; Bagci, Binnur; Gumus, Erkan; Ozdemir, Ozturk (IRANIAN SOC NEPHROLGY, 2015)Introduction. It has been shown that gene polymorphisms influence the development and progression of chronic kidney disease (CKD). Many studies have indicated that aldosterone synthase CYP11B2 gene polymorphism (-344C>T) ... -
Angiotensin-Converting Enzyme (ACE) I/D and Alpha-Adducin (ADD1) G460W Gene Polymorphisms in Turkish Patients with Severe Chronic Tinnitus
Yuce, Salim; Sancakdar, Enver; Bagci, Gokhan; Koc, Sema; Kurtulgan, Hande Kucuk; Bagci, Binnur; Dogan, Mansur; Uysal, Ismail Onder (AVES, 2016)OBJECTIVE: Tinnitus is described as a disturbing sound sensation in the absence of external stimulation. We aimed to investigate whether there is any relationship between severe chronic tinnitus and angiotensin-converting ... -
Apelin and fetuin-a may be subclinical inflammation biomarker in familial mediterranean fever: A pilot study
Sahin, Ali; Demirpence, Ozlem; Sahin, Mehtap; Bagci, Gokhan; Seven, Dogan; Dogan, Halef Okan; Camci, Ayse; Derin, Mehmet Emin; Bagci, Binnur (DERMAN MEDICAL PUBL, 2017)Aim: Positive acute-phase reactants generally increase during the attack period (AP) of familial Mediterranean fever (FMF) and return to normal range in the attack-free period (AFP). In some patients, the level of these ... -
Association of vitamin D receptor gene Taql, Fokl and Apal variants with arteriovenous fistula failure in hemodialysis patients
Huzmeli, Can; Bagci, Gokhan; Candan, Ferhan; Bagci, Binnur; Akkaya, Lale; Kayatas, Mansur (SAGE PUBLICATIONS LTD, 2018)Purpose: We investigated the influence of the vitamin D receptor gene Taql (rs731236), Apal (rs7975232), and Fokl (rs2228570) polymorphisms in arteriovenous fistula failure in hemodialysis patients. Methods: This study was ... -
Associations of fractalkine receptor (CX3CR1) and CCR5 gene variants with hypertension, diabetes and atherosclerosis in chronic renal failure patients undergoing hemodialysis
Bagci, Binnur; Bagci, Gokhan; Huzmeli, Can; Sezgin, Ilhan; Ozdemir, Ozturk (SPRINGER, 2016)We aimed to investigate the associations of fractalkine receptor (CX3CR1) V249I, T280M and CCR5-59029 A/G gene polymorphisms in chronic renal failure (CRF) subjects undergoing hemodialysis and to evaluate possible associations ... -
Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients
Yilmaz, Meral; Elaldi, Nazif; Bagci, Binnur; Sari, Ismail; Gumus, Erkan; Yelkovan, Izzet (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015)Objective: In this case-control study, we investigated whether IL-6 (-174G/C) and TNF-alpha (-308G/A) gene polymorphisms affect the clinical course and outcome of CCHF. Methods: Total 150 patients with CCHF and 170 controls ... -
Evaluation of 61 Secondary Amyloidosis Patients: A Single-Center Experience from Turkey
Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Alaygut, Demet; Bagci, Binnur; Yildiz, Esin; Kockara, Ayse Seker; Kayatas, Mansur (DERMAN MEDICAL PUBL, 2016)Aim: To evaluate demographic,clinical and laboratory characteristics. causes, MEFV gene mutations, and mortality rates of patients with secondary amyloidosis. Material and Method: 61 patients who had been diagnosed with ... -
Frequency of familial Mediterranean fever (MEFV) gene mutations in patients with biopsy-proven primary glomerulonephritis
Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Alaygut, Demet; Yilmaz, Ali; Gedikli, Asim; Bagci, Binnur; Timucin, Meryem; Sezgin, Ilhan; Kayatas, Mansur (SPRINGER LONDON LTD, 2017)Primary glomerulopathies are those disorders that affect glomerular structure, function, or both in the absence of a multisystem disorder. We aimed to evaluate the frequency of MEFV gene mutation to show possible coexistence ... -
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer
Oz, Muhammed; Karakus, Savas; Yildirim, Malik; Bagci, Binnur; Sari, Ismail; Bagci, Gokhan; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali; Yanik, Ali (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2018)Aim: Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial ... -
Glutathione-S-Transferase Variants are not Associated With Increased Carotid Intima-Media Thickness in Turkish Familial Mediterranean Fever Patients
Gurbuz, Ozlem; Bagci, Binnur; Huzmeli, Can; Bagci, Gokhan; Candan, Ferhan (TURKISH LEAGUE AGAINST RHEUMATISM, 2016)Objectives: This study aims to evaluate the carotid intima-media thickness (CIMT) in patients diagnosed with familial Mediterranean fever (FMF) and investigate whether there is a relationship between glutathione-S-transferase ... -
KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients
Bagci, Binnur; Sari, Musa; Karadayi, Kursat; Turan, Mustafa; Ozdemir, Ozturk; Bagci, Gokhan (IOS PRESS, 2016)BACKGROUND: Colorectal cancer is a serious disease that causes significant morbidity and mortality in developed countries. Genetic changes, such as mutations in proto-oncogenes and DNA repair genes, and loss of function ... -
Prevalence of Fabry Disease in Familial Mediterranean Fever Patients from Central Anatolia of Turkey
Huzmeli, Can; Candan, Ferhan; Alaygut, Demet; Bagci, Gokhan; Akkaya, Lale; Bagci, Binnur; Sozmen, Eser Yildirim; Kurtulgan, Hande Kucuk; Kayatas, Mansur (SPRINGER/PLENUM PUBLISHERS, 2016)Fabry disease (FD) is a progressive, X-linked inherited disorder of glycosphingolipid metabolism due to deficient or absent lysosomal alpha-galactosidase A (AGALA) activity. FD and familial Mediterranean fever (FMF) have ... -
The protective effect of MCP-1-2518 A > G promoter polymorphism in Turkish chronic renal failure patients requiring long-term hemodialysis
Bagci, Binnur; Bagci, Gokhan; Candan, Ferhan; Ozdemir, Ozturk; Sezgin, Ilhan (SPRINGER, 2015)Monocyte chemoattractant protein-1 (MCP-1) plays a major role in the pathogenesis and progression of different types of human renal disease. Therefore, in this study, we aimed to investigate the effect of MCP-1 gene -2518 ... -
Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range
Elaldi, Nazif; Yilmaz, Meral; Bagci, Binnur; Yelkovan, Izzet; Bagci, Gokhan; Gozel, Mustafa Gokhan; Engin, Aynur; Bakir, Mehmet; Dokmetas, Ilyas (WILEY, 2016)Crimean-Congo hemorrhagic fever (CCHF) is a fatal emerging acute viral infection. Not much is known regarding the pathogenic mechanisms and the reasons behind severe or mild disease courses in CCHF. IFN-alpha (IFNA) is one ... -
Renalase gene polymorphism is associated with increased blood pressure in preeclampsia
Bagci, Binnur; Karakus, Savas; Bagci, Gokhan; Sancakdar, Enver (ELSEVIER SCI LTD, 2016)Background: Renalase is a novel enzyme that degrades circulating catecholamines. We aimed to investigate the role of rs2576178 and rs10887800 polymorphisms of the renalase gene in preeclampsia (PE) patients Methods: This ... -
SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia
Karakus, Savas; Bagci, Binnur; Bagci, Gokhan; Sancakdar, Enver; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali (TAYLOR & FRANCIS INC, 2017)Objective: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE).Methods: In total, 89 ... -
VEGF, sVEGFR-1 and Endostatin Serum Levels and VEGF Polymorphisms in Recurrent Aphthous Stomatitis
Yuce, Salim; Bagci, Binnur; Bagci, Gokhan; Dogan, Mansur; Koc, Sema; Sezgin, Ilhan; Candan, Ferhan; Uysal, Ismail Onder (DERMAN MEDICAL PUBL, 2016)Aim: Recurrent aphthous stomatitis (RAS) is one of the most frequent diseases of the oral mucosa, characterized by chronic, painful, recurrent, and necrotizing ulcerations. The precise etiology and pathogenesis of RAS have ... -
VITAMIN D RECEPTOR TAQI POLYMORPHISM IS ASSOCIATED WITH HIGHER IMMUNE RESPONSE TO HEPATITIS B VACCINATION IN TURKISH DIALYSIS PATIENTS
Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Bagci, Binnur; Akkaya, Lale; Seker, Ayse; Kayatas, Mansur (CARBONE EDITORE, 2018)Introduction: We aimed to investigate the possible role of vitamin D receptor (VDR) gene TaqI, ApaI and FokI polymorphisms in immune response to Hepatitis B virus (HBV) vaccination in dialysis patients. Methods: A total ...