Browsing Beslenme ve Diyetetik Bölümü Makale Koleksiyonu by Issue Date
Now showing items 1-20 of 58
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Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(MDPI, 01.12.2023)Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body. Objectives: In this study, we aimed to investigate the relationship between ... -
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(02.10.2023)In this study aimed to the synthesis of novel bis-nicotinonitrile derivatives starting from 1,3-bis-chalcones and investigate their antimicrobial activity potentials. Bis-nicotinonitrile derivatives were synthesized ... -
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ... -
In vitro cytotoxic effects, in silico studies, some metabolic enzymes inhibition, and vibrational spectral analysis of novel β-amino alcohol compounds
(Elsevier, 05.02.2023)In this study, an efficient single-step method for the preparation of β-amino alcohols ( 1 –3 ) in aqueous media was applied. The aim was to investigate the cytotoxic activity of Compounds 1, 2 and 3 in neu- roblastoma ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)The main aims of anticancer drug development studies is to reduce the toxicity of the developed compound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)The main aims of anticancer drug development studies is to reduce the toxicity of the developed com- pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 05.09.2023)We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ... -
Synthesis and Caracterizations of New Thiosemicarbazone and Thiazole Derivatives From Polycyclic Chiral 1,5- Diketones
(08.11.2023)Thiosemicarbazone derivatives have a wide spectrum of biological activity as well as various application areas such as forming complexes with metals, using as intermediates in the synthesis of heterocyclic bioactive ... -
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 15.09.2023)Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The resin obtained from this plant is effective for different diseases. The chemical content of the ethanol extract ... -
Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies
(15.11.2023)Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin (ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by Fourier Transform Infrared Spectrophotometry (FTIR) ... -
Sensorial and Nutritional Properties of a Collagen-Fortified Snack Bar Designed for the Elderly
(MDPI, 17.08.2023)Background: This study aimed to develop a highly consumable collagen-containing bar that contributes to enriching the diets of elderly individuals, in terms of energy and nutrients. Method: For this purpose, five different ... -
Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
(De Gruyter, 2021)Objectives: The aim of this study was to investigate BAP1, OGT and YY1 genes and protein levels in 12 samples (8 males, 4 females) of eyelid tumor tissue with basal cell carcinoma (BCC) and 12 normal control subjects ... -
INVESTIGATION OF THE ANTIMICROBIAL AGENT POTENTIAL OF 1,5-DIKETONE DERIVATIVES
(2021)In this study, 1,5-diketones were synthesized by adding of cyclohexanone to five different chalcone derivatives (1a-e) via the 1,4-Michael addition reaction. Antimicrobial activities of synthesized compounds were investigated ... -
Cytotoxic effect, spectroscopy, DFT, enzyme inhibition, and moleculer docking studies of some novel mesitylaminopropanols: Antidiabetic and anticholinergics and anticancer potentials
(Elsevier, 2021)b-Amino alcohols (2–4) used in this study were re-synthesized in accordance with our previous study. All compounds were characterized by the combination of NMR, UV–Vis, IR experimental and theoretical spectral data. Then, ... -
IL‑13 Gene Polymorphisms (‑1112 C/T and ‑1512 A/C) in Patients with Chronic and Aggressive Periodontitis: Effects on GCF and Outcome of Periodontal Therapy
(Medical and Dental Consultants’ Association of Nigeria, 2021)Background: IL‑13 is the key cytokine in the regulation of inflammatory with an autoimmune disease and has an anti‑inflammatory effect. Aims: This study aimed to compare IL‑13 (‑1112 C/T and ‑1512 A/C) gene polymorphisms in ... -
Michael/Michael Addition Cascade of 2-Benzylidene-1- indanones with Chalcones: Synthesis and Biological Evaluations of Novel Polycyclic Compounds
(2021)A series of novel racemic 2-aryloyl-1,3-diaryl-2,3,3a,8a-tetrahydrocyclopenta[a]inden-8(1H)-one derivatives were synthesized from KOtBu mediated Michael/Michael addition reaction of 2-benzylidene-1-indanones with chalcones ... -
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(2021)A new class of cyanopyridine derivatives (10a-e and 11a-e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ... -
Synthesis of PEGylated nanographene oxide as a nanocarrier for docetaxel drugs and anticancer activity on prostate cancer cell lines
(SAGE Publishing, 2021)Graphene oxide (GO) has recently been considered one of the most promising carbon derivatives in nanotechnology. It has many excellent features such as tumor targeting ability, biocompatibility and low toxicity. Therefore, ... -
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ... -
In vitro evaluation of probiotic potential of Enterococcus faecium strains isolated from Turkish pastirma
(SPRINGER, 2021)This study is aimed at evaluating the probiotic potential of three Enterococcus faecium strains (called 29-P2, 168-P6 and 277-S3) isolated from ‘pastırma’, a Turkish traditional dry-cured meat product. For this, key ...