Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Language "eng"
Now showing items 1-20 of 58
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A porous fabric-based molecularly imprinted polymer for specific recognition of tetracycline by radiation-induced RAFT-mediated graft copolymerization
(October 20)Despite technical and methodological advances, the selective separation of antibiotics from aqueous media remains a challenge. In this work, a novel molecularly imprinting polymer (MIP) with specific recognition sites was ... -
ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
(April, 202)Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is aimed ... -
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
(ELSEVİER, 2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
(December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
(April 2022)Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential ... -
Application of a new dithizone grafted polymeric adsorbent for solid phase microextraction of manganese and copper prior to FAAS in fortified vegetables and barbecue samples
(13.06.2022)A new potential solid phase material called as dithizone@PAA was synthesized for first times, characterized and utilized as an easy versatile polymeric sorbent for the shake-assisted dispersive solid-phase micro-extraction ... -
Application of cloud point extraction for residues of chloramphenicol and amoxicillin in milk samples by HPLC–DAD
(Springer, 2022)A pre-concentration and sensitive determination method for residues of Chloramphenicol (CLP) and Amoxicillin (AMX) in milk samples were developed based on cloud point extraction (CPE) and HPLC–DAD analysis. CLP and AMX ... -
Application of magnetic solid‑phase extraction for sensitive determination of anticancer drugs in urine by means of diamino benzidine tetrachlorohydrate modified magnetic nanoparticles
(Şubat, 202)Background The analysis of drug active molecules and residues in the treatment of cancer is important for the sustainability of human life and therapeutic effects. For this purpose, a new magnetic sorbent was developed ... -
Arylated quinoline and tetrahydroquinolines: Synthesis, characterization and their metabolic enzyme inhibitory and antimicrobial activities
(Chemstry Europa, 2022/10/07)The aims of this study are to synthesize and characterize some new phenyl quinoline derivatives and to determine the activities of them and the recently prepared substituted phenyl quinolines against Acetylcholinesterase ... -
Azinphos-methyl and chlorfenvinphos pesticides determination using fabric phase sorptive extraction followed by high performance liquid chromatography-photodiode array detector
(Elsevier, 25 April 2)A reliable and efficient fabric phase sorptive extraction method was developed for the rapid analysis of azinphosmethyl and chlorfenvinphos pesticide residues in wastewater and fruit juice samples using high-performance liquid ... -
Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
(Elsevier, 14.08.2022)Based on the biologically active heterocycle compounds, a series of new benzimidazole-hydrazone deriva- tives ( 3a-3j ) were synthesized, starting from 4-(6-chloro-1 H -benzimidazol-2-yl) benzohydrazide. The syn- thesized ... -
Biological effects and molecular docking studies of Catechin 5-O-gallate: Antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Taylor & Francis, 2022/04/13)Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ... -
Biologically active phthalocyanine metal complexes: Preparation, evaluation of α‐glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies
(Wiley-VCH GmbH, Weinheim, 2021/6)In this study, preparation, as well as investigation of α‐glycosidase and cholinesterase (ChE) enzyme inhibition activities of furan‐2‐ylmethoxy‐substituted compounds 1–7, are reported. Peripherally, tetra‐substituted ... -
Composition characterization and biological activity study of Achillea vermicularis extract and extract‐loaded nanoparticles
(JUMB, 2023/1/9)Antiproliferative activity of Achillea vermicularis extracts was calculated on glial (C6) and keratinocyte (HaCaT) cell lines using XTT assay. It was observed that all extracts of A. vermicularis at the determined concentration ... -
Decolourization of Methylene Blue in Aqueous Solution by Photocatalytic Oxidation, Fenton Oxidation and Biosorption
(Cumhuriyet Science Journal, 27.12.2022)The aim of the study was to investigate decolourization of Methylene Blue (MB) in aqueous solution using advanced oxidation processes (AOPs) and biosorption comparatively. Photocatalytic decolourization of MB was studied ... -
Decoration, Characterization and Antimicrobial Activity Evaluation of Novel Nano-Based 1,2-Phenylenediamine Functionalized Maleic Anhydride-Allylphenyl Ether Conjugate
(Chemistry Europe, 02 October)1,2-Phenylenediamine (o-PDA) is a well-known fluorescent dye that enables the decoration of next generation chemotherapeutics. A novel o-PDA-functionalized maleic anhydride-allyl phenyl ether (poly(MA-alt-APE)/o-PDA ... -
Deep Eutectic Solvent-based Extraction of As, Mn, Pb, Cr, and Ni from Spleen, Kidney, and Brain Samples
(14 Septemb)Deep eutectic solvent extraction for As, Mn, Pb, Cr, and Ni from spleen, kidney, and brain samples was investigated. The experimental parameters such as type and amount of deep eutectic solvent and sample/deep eutectic ... -
Design, synthesis and biological evaluation of novel ketone derivatives containing benzimidazole and 1,3,4-triazole as CA inhibitors
(03.10.2023)In this study, we synthesized a series of new benzimidazole-triazole (6a-6k) derivatives and characterized them by 1 H NMR, 13C NMR, and HRMS. These compounds were evaluated for their inhibitory activity against hCA-I and ... -
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
(Medicinal Chemistry Research, 08.08.2022)In this study, eleven new compounds with a series of benzimidazole-1,3,4-oxadiazole derivatives structures were synthesized and evaluated for their human (h) carbonic anhydrase inhibitory activities against two isoforms ... -
Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
(Elsevier, 2022/09/15)Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone ...