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Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
(Elsevier, 2023/12/1)
In the present work, a series of compounds containing imidazole and hydrazone structural frameworks were synthesized and characterized using various spectral techniques, including 1H NMR, 13C NMR, FTIR, and HRMS. Synthesized ...
Propolis nanoparticles synthesis and characterization with cytotoxic and apoptotic effects on breast cancer cells
(2023)
The aim of this work was to investigate the antiproliferative and pro-apoptotic effects of propolis
on human breast cancer cells using a simple and inexpensive nanoformulation. Various meth ods were used to characterize ...
Imidazole‐hydrazone derivatives: Synthesis, characterization, X‐ray structures and evaluation of anticancer and carbonic anhydrase I–II inhibition properties
(Chemistry Europe, 2023/7/20)
The nine new imidazole-hydrazone derivatives of Schiff base
were synthesized from the condensation reactions of 1-methyl1H-imidazole-2-carbaldehyde with various substitutedhydrazide derivatives. Structures of the final ...
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)
Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate
(DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ...
Isatin/thiosemicarbohydrazone hybrids: Facile synthesis, and their evaluation as anti-proliferatıve agents and metabolıc enzyme inhibitors
(AJOL, 2023/7/3)
We are reporting a novel series of thiosemicarbazone derivatives derived from isatin (1-6), structural determination, and investigation of the inhibitory properties against proliferative, carbonic anhydrase, and cholinesterase ...
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)
The combination of a commercially available PGLA
(poly[glycolide-co-L-lactide]), 90:10% suture material with bio active bioglass nanopowders (BGNs) and graphene oxide (GO)-
doped BGNs offers new opportunities for the ...
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(2023)
Mushrooms, which have been collected to meet the nutritional needs of the world for many years,
have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies
carried out to determine ...
New Fluoro- and Trifluoromethyl-Substituted Trimethoxychalcones as Anticancer Agents: Synthesis, Bioevaluation, and Computational Studies
(2023)
We designed and synthesized a novel series of trimethoxy
chalcones with CF3 or F substituents at various positions of ring
B, characterized using IR, NMR spectral data, and elemental
analyses, based on the fact that ...
Plant‑inspired adhesive and injectable natural hydrogels: in vitro and in vivo studies
(2023)
The development of alternative thera peutic treatments based on the use of medicinal and
aromatic plants, such as Juniper communis L., has
aroused interest in the medical feld to fnd new alter natives to conventional ...
Composition characterization and biological activity study of Achillea vermicularis extract and extract‐loaded nanoparticles
(JUMB, 2023/1/9)
Antiproliferative activity of Achillea vermicularis extracts was calculated on glial (C6) and keratinocyte (HaCaT) cell lines using XTT assay. It was observed that all extracts of A. vermicularis at the determined concentration ...