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Potent In Vitro Phosphodiesterase 1 Inhibition of Flavone Isolated from Pistacia integerrima Galls
(biomed research international, 2022)
To prospect an isozyme-specific, effective inhibitor against the physiologically-crucial enzyme phosphodiesterase 1 (PDE1),
phytochemicals from Pistacia integerrima galls were screened. The chloroform fraction of gall ...
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives
(oxidative medicine and cellular longevity, 2022)
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal
sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of ...
A Review on Tradescantia: Phytochemical Constituents, Biological Activities and Health-Promoting Effects
(Frontiers in Bioscience landmark, 2022)
Tradescantia is a genus of herbaceous and perennial plants belonging to the Commelinaceae family and organized into three infrageneric
classifications and 12 sections. More than 80 species within the genus have been used ...
The role of Tumour Necrosis Factor in neuroinflammation associated with Parkinson's disease and targeted therapies
(neurochemistry international, 2022)
Neurodegenerative disorders Parkinson’s disease is a progressive neurodegenerative disorder associated with
neuroinflammatory responses that lead to the neurodegeneration of the dopaminergic neurons. These neuroinflammatory ...
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
(biomed research international, 2022)
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is
now growing scientific evidence to support the effectiveness of the use of herbal ...
Biosynthesis of Secondary Metabolites Based on the Regulation of MicroRNAs
(biomed research international, 2022)
MicroRNA (miRNA), a noncoding ribonucleic acid, is considered to be important for the progression of gene expression in plants
and animals by rupture or translational repression of targeted mRNAs. Many types of miRNA ...
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
(2023)
The cytotoxic activities of the compounds were determined by the 3‐(4,
5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human
breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
(2023)
Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse
model.
Materials and Methods: Five groups were formed with eight ...
Chemical and functional composition and biological activities of Anatolian Hypericum scabrum L. plant
(2023)
Hypericum scabrum L. plant has wide use in ethnopharmacology and is cultivated both naturally and technologically. This study was conducted to determine chemical and functional properties and in vitro biological activities ...
Synthesis of novel Cu(II) complexes with N2O2 ligands: Characterization, theoretical calculations, antimicrobial, antioxidant, DNA binding, and in vitro anticancer activity studies
(2023)
The aim was to investigate the in vitro antimicrobial, antioxidant, cytotoxic activities and pBR322 Plasmid DNA interaction potentials of newly synthesized Schiff bases and their copper complexes. Cytotoxic activities of ...